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Transcutaneous Vagal Nerve Stimulation (tVNS)

DEVICE11 trials

Sponsors

Emory University, Charles Ethan Paccione, M.S., M.A., University of Florida, Istituto Clinico Humanitas, Maastricht University Medical Center

Conditions

ActionAgingAutonomic DysfunctionChronic Obstructive Pulmonary Disease SevereChronic Widespread PainCognitionCognitive PerformanceDyspnea

Phase 2

Role of Sympathetic Overactivity and Angiotensin II in PTSD and CV
SuspendedNCT02560805
Emory UniversityStress Disorders, Post-Traumatic
Start: 2015-10-31End: 2026-02-28Target: 134Updated: 2025-03-05

Unknown Phase

Sympathetic Overactivity in Post-traumatic Stress Disorder
RecruitingNCT01627301
Emory UniversityPost-traumatic Stress Disorder, Prehypertension
Start: 2012-07-31End: 2027-12-31Target: 120Updated: 2026-01-15
The Predictive Value of Transcutaneous VNS for Effect of an Implanted VNS System in Epilepsy Patients
Active, not recruitingNL-OMON42025
Medisch Spectrum Twenteneurologische aandoeningen, hersenaandoeningen, epilepsie epilepsy epileptic seizure
Start: 2015-08-25Target: 15Updated: 2024-02-28
Body Versus Machine: Deep Breathing Versus Vagus Stimulation for the Treatment of Fibromyalgia
CompletedNCT03180554
Charles Ethan Paccione, M.S., M.A.Chronic Widespread Pain, Fibromyalgia
Start: 2019-03-15End: 2020-10-09Updated: 2022-01-04
Non-invasive Nerve Stimulation and Cognitive Training to Improve Cognitive Performance in Healthy Older Adults
Active, not recruitingNCT04276805
University of FloridaAging
Start: 2020-11-17End: 2025-10-30Updated: 2025-05-01
Home Operations Utilizing Stimulation
CompletedNCT04484285
University of FloridaCognitive Performance
Start: 2020-08-20End: 2023-09-06Updated: 2025-04-20
Long-term Effects of Transcutaneous Vagal Nerve Stimulation on Postural Orthostatic Tachycardia Syndrome (POTS)
NCT04632134
Istituto Clinico HumanitasAutonomic Dysfunction, Orthostatic Intolerance, Physical Disability +2
Start: 2019-11-10End: 2022-12-30Target: 23Updated: 2022-06-30
Neural Correlates of tVNS
NCT04810234
Maastricht University Medical CenterfMRI, Nucleus of the Solitary Tract (NTS), Transcutaneous Vagal Nerve Stimulation (tVNS)
Start: 2020-11-01End: 2021-06-01Target: 16Updated: 2021-03-22
The Path Study: Cognitive and Inflammation Targeted Gut-brain Interventions in Alcohol; Probiotics, Alcohol, Transcutaneous Vagus Nerve Stimulation, and HIV Study
RecruitingNCT05090267
University of FloridaCognition, Gut Microbiome
Start: 2022-06-01End: 2026-06-30Target: 80Updated: 2025-06-15
Alleviating Dyspnea With Non-Invasive Neuromodulation
CompletedNCT06985628
Université de SherbrookeChronic Obstructive Pulmonary Disease Severe, Dyspnea
Start: 2024-11-18End: 2025-12-10Updated: 2026-02-24
Neural Bases of Motivation
RecruitingNCT07251816
Hospices Civils de LyonAction, Healthy Volunteers, Motivation
Start: 2026-01-14End: 2033-01-01Target: 204Updated: 2026-01-22

Related Papers

Non-invasive neuromodulation for alleviating dyspnoea: protocol for a feasibility sham-controlled randomised trial
BMJ Open2025-07-01
Meditative-based diaphragmatic breathing vs. vagus nerve stimulation in the treatment of fibromyalgia—A randomized controlled trial: Body vs. machine
Frontiers in Neurology2022-11-0329 citations
Motivational nondirective resonance breathing versus transcutaneous vagus nerve stimulation in the treatment of fibromyalgia: study protocol for a randomized controlled trial.
2020-09-236 citations