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Tiotropium + Olodaterol

DRUG9 trials

Sponsors

Boehringer Ingelheim, Queen's University

Conditions

Chronic Obstructive Pulmonary DiseasePulmonary Disease, Chronic Obstructive

Phase 3

Tiotropium+Olodaterol Fixed Dose Combination (FDC) Versus Tiotropium and Olodaterol in Chronic Obstructive Pulmonary Disease (COPD)
CompletedNCT01431274
Boehringer IngelheimPulmonary Disease, Chronic Obstructive
Start: 2011-09-30End: 2013-09-30Updated: 2015-07-16
Tiotropium +Olodaterol Fixed Dose Combination (FDC) Versus Tiotropium and Olodaterol in Chronic Obstructive Pulmonary Disease (COPD)
CompletedNCT01431287
Boehringer IngelheimPulmonary Disease, Chronic Obstructive
Start: 2011-09-30End: 2013-11-30Updated: 2015-07-16
Effect on Exercise Endurance and Lung Hyperinflation of Tiotropium + Olodaterol in COPD Patients.
CompletedNCT01533935
Boehringer IngelheimPulmonary Disease, Chronic Obstructive
Start: 2012-02-29End: 2013-11-30Updated: 2015-09-15
Effect on Exercise Endurance and Lung Hyperinflation of Tiotropium + Olodaterol in COPD Patients
CompletedNCT01533922
Boehringer IngelheimPulmonary Disease, Chronic Obstructive
Start: 2012-03-31End: 2013-11-30Updated: 2015-09-15
Effect on Exercise Endurance and Lung Hyperinflation of Tiotropium + Olodaterol in COPD Patients
CompletedNCT01533922
Boehringer IngelheimPulmonary Disease, Chronic Obstructive
Start: 2012-03-31End: 2013-11-30Updated: 2015-09-15
Effect on Exercise Endurance and Lung Hyperinflation of Tiotropium + Olodaterol in COPD Patients.
CompletedNCT01533935
Boehringer IngelheimPulmonary Disease, Chronic Obstructive
Start: 2012-02-29End: 2013-11-30Updated: 2015-09-15
Japan Long-term Safety for Tiotropium Plus Olodaterol
CompletedNCT01536262
Boehringer IngelheimPulmonary Disease, Chronic Obstructive
Start: 2012-02-29End: 2013-09-30Updated: 2015-07-15
Characterization of 24-hour Lung Function Profiles of Inhaled Tiotropium + Olodaterol Fixed Dose Combination in Patients Suffering From Chronic Obstructive Pulmonary Disease
CompletedNCT01559116
Boehringer IngelheimPulmonary Disease, Chronic Obstructive
Start: 2012-03-31End: 2013-08-31Updated: 2015-07-16

Phase 4

Effects of Dual Bronchodilator Treatment on Cardiopulmonary Interactions in COPD
CompletedNCT03425617
Queen's UniversityChronic Obstructive Pulmonary Disease
Start: 2017-01-01End: 2018-06-30Updated: 2019-02-05
A Study to Test the Combination of Tiotropium and Olodaterol Using the Respimat® Inhaler in People With Chronic Obstructive Pulmonary Disease (COPD) Who Have Different Abilities to Inhale
CompletedNCT04223843
Boehringer IngelheimPulmonary Disease, Chronic Obstructive
Start: 2020-01-08End: 2020-09-29Updated: 2021-11-18

Unknown Phase

A Study in Taiwan Based on Medical Records That Looks at the Occurrence of Flare-ups in Patients With Chronic Obstructive Pulmonary Disease (COPD) Who Started LABA/LAMA or LAMA Treatment
CompletedNCT04011475
Boehringer IngelheimPulmonary Disease, Chronic Obstructive
Start: 2019-12-29End: 2020-10-31Updated: 2022-06-14

Related Papers

Tiotropium/Olodaterol Delays Clinically Important Deterioration Compared with Tiotropium Monotherapy in Patients with Early COPD: a Post Hoc Analysis of the TONADO® Trials
Advances in Therapy2020-11-1113 citations
Blood eosinophils as a biomarker of future COPD exacerbation risk: pooled data from 11 clinical trials.
2020-09-1738 citations
Tiotropium/Olodaterol Decreases Exacerbation Rates Compared with Tiotropium in a Range of Patients with COPD: Pooled Analysis of the TONADO<sup>®</sup>/DYNAGITO<sup>®</sup> Trials.
2020-08-1011 citations
&lt;p&gt;No Influence on Cardiac Arrhythmia or Heart Rate from Long-Term Treatment with Tiotropium/Olodaterol versus Monocomponents by Holter ECG Analysis in Patients with Moderate-to-Very-Severe COPD&lt;/p&gt;
International Journal of COPD2020-08-016 citations
&lt;p&gt;Absence of Adverse Effects of Tiotropium/Olodaterol Compared with the Monocomponents on Long-Term Heart Rate and Blood Pressure in Patients with Moderate-to-Very-Severe COPD&lt;/p&gt;
International Journal of COPD2020-08-015 citations
Efficacy of Tiotropium/Olodaterol Compared with Tiotropium as a First-Line Maintenance Treatment in Patients with COPD Who Are Naïve to LAMA, LABA and ICS: Pooled Analysis of Four Clinical Trials
Advances in Therapy2020-07-1522 citations
Benefits of Tiotropium/Olodaterol Compared with Tiotropium in Patients with COPD Receiving only LAMA at Baseline: Pooled Analysis of the TONADO<sup>®</sup> and OTEMTO<sup>®</sup> Studies.
2020-05-276 citations
The effect of tiotropium/olodaterol versus tiotropium on COPD exacerbation rates in patients with/without frequent exacerbation history
2019-09-282 citations
Benefits of tiotropium/olodaterol compared with tiotropium in patients with COPD receiving only LAMA at baseline: pooled analysis of 4 clinical trials
2019-09-28
Effect of tiotropium/olodaterol combination therapy on long-term heart rate and blood pressure in COPD patients
2018-09-151 citations
Safety of tiotropium/olodaterol in chronic obstructive pulmonary disease: pooled analysis of three large, 52-week, randomized clinical trials
Respiratory Medicine2018-08-2823 citations
Long-term safety of tiotropium/olodaterol Respimat<sup>®</sup> in patients with moderate-to-very severe COPD and renal impairment in the TONADO<sup>®</sup> studies.
2018-06-014 citations
Long-Term Safety of Tiotropium/Olodaterol Respimat in Patients with Moderate-to-Very Severe COPD and Renal Impairment in the TONADO Studies
Pneumologie2018-02-211 citations
Long-Term Safety of Tiotropium/Olodaterol Respimat in Elderly Patients with Moderate to Very Severe COPD in the TONADO Studies
Pneumologie2018-02-21
β-Blockers in COPD: A Cohort Study From the TONADO Research Program.
2018-01-3122 citations
Impact of grouping patients by 2017 GOLD strategy assessment criteria: a post hoc analysis of the TONADO and OTEMTO trials
2017-09-011 citations
The impact of grouping patients by the 2017 GOLD COPD strategy on response to therapy: post hoc results from the TONADO tiotropium+olodaterol trials
2017-09-01
Effects of Symptom Severity at Baseline on Lung-Funktion and SGRQ Responses in the OTEMTO Studies
Pneumologie2017-02-23
P296 Effect of tiotropium/olodaterol therapy on copd exacerbations in the tonado® studies
Thorax2016-11-153 citations
P294 Benefits of tiotropium/olodaterol over tiotropium at delaying clinically significant events in patients with copd classified as gold B
Thorax2016-11-152 citations

16 more papers not shown