Therapeutic plasma exchange

DEVICE14 trials

Conditions

ARDSAcute Respiratory Distress SyndromeAcute Respiratory FailureAgingAutoimmune DiseasesCOVID-19COVID-19 PneumoniaCOVID-19 Respiratory Infection

Phase 1

Therapeutic Plasma Exchange in Adult Patients With Severe Sepsis

CompletedNCT04057872

Alberta Health Services, CalgarySeptic Shock

Start: 2020-10-21End: 2024-12-31Updated: 2025-10-03

Measurement of IL-6 and Secondary Inflammatory Markers Before and After Therapeutic Plasma Exchange (TPE) in Hospitalized Patients

NCT04592705

Larkin Community HospitalCOVID-19

Start: 2020-09-11End: 2021-08-30Target: 10Updated: 2020-10-19

Phase 2

Therapeutic Plasma Exchange Alone or in Combination With Ruxolitinib in COVID-19 Associated CRS

CompletedNCT04374149

Prisma Health-UpstateCOVID19, Cytokine Release Syndrome

Start: 2020-04-30End: 2020-12-01Updated: 2021-12-02

Therapeutic Plasma Exchange in Septic Shock: A Pilot Study

RecruitingNCT05093075

University of ManitobaSeptic Shock

Start: 2023-06-01End: 2027-12-31Target: 80Updated: 2025-08-17

Autoantibody Reduction Therapy for Progressive Idiopathic Pulmonary Fibrosis

Not yet recruitingNCT07674745

University of Alabama at BirminghamIdiopathic Pulmonary Fibrosis

Start: 2026-10-01End: 2031-03-31Target: 52Updated: 2026-07-01

Phase 3

Evaluation of Therapeutic Plasma Exchange (TPE) Procedure Using the AMICUS Device

CompletedNCT01210716

Fenwal, Inc.Autoimmune Diseases, Hematologic Disorders, Oncologic Disorders +1

Start: 2010-09-30End: 2011-05-31Updated: 2013-09-23

Plasma Exchange in Covid-19 Patients With Anti-interferon Autoantibodies

NCT05182515

Centre Hospitalier St AnneCOVID-19

Start: 2021-12-22End: 2022-03-22Target: 50Updated: 2022-01-10

The Effects Of Therapeutic Plasma Exchange (TPE) On Age Related Biomarkers And Epigenetics

Active, not recruitingNCT06534450

Dobri KiprovAging

Start: 2022-09-12End: 2025-08-31Updated: 2024-08-02

Unknown Phase

Therapeutic Plasma Exchange in the Treatment of Sepsis Associated Multi-Organ Failure [SAMOF-TPE]

NCT03844542

Forsyth Medical CenterSepsis

Start: 2019-06-30End: 2023-06-30Target: 300Updated: 2019-02-18

Therapeutic Plasma Exchange for Coronavirus Disease-2019 Triggered Cytokine Release Storm;

CompletedNCT04485169

UNICEFCOVID-19, Cytokine Release Syndrome

Start: 2020-04-01End: 2020-07-31Updated: 2020-09-28

Therapeutic Plasma Exchange in Thyrotoxicosis

CompletedNCT04485975

Baskent UniversityThyrotoxicosis

Start: 1999-01-01End: 2020-04-01Updated: 2020-07-24

Investigational Treatments for COVID-19 in Tertiary Care Hospital of Pakistan

CompletedNCT04492501

UNICEFARDS, Covid19, Critical Illness +1

Start: 2020-04-01End: 2020-07-20Updated: 2020-07-30

RescuE pLAsma eXchange in Severe COVID-19

TerminatedNCT04685655

Heidelberg UniversityCovid19, Therapeutic Plasma Exchange

Start: 2020-01-07End: 2023-04-30Updated: 2025-04-15

Therapeutic Plasma Exchange Followed by Convalescent Plasma Transfusion in Severe and Critically Ill COVID-19 Patients

CompletedNCT04973488

Novacescu AlexandruAcute Respiratory Distress Syndrome, Acute Respiratory Failure, COVID-19 Pneumonia +1

Start: 2020-07-25End: 2021-01-10Updated: 2024-08-26

Related Papers

Multi‐Omics Analysis Reveals Biomarkers That Contribute to Biological Age Rejuvenation in Response to Single‐Blinded Randomized Placebo‐Controlled Therapeutic Plasma Exchange

Aging Cell2025-05-276 citations

Treatment with therapeutic plasma exchange in severe COVID-19 pneumonia: A case report and review of the literature.

2022-01-213 citations

Therapeutic plasma exchange followed by convalescent plasma transfusion in severe and critically ill COVID‑19 patients: A single centre non‑randomized controlled trial

Experimental and Therapeutic Medicine2021-11-2411 citations

Efficacy of therapeutic plasma exchange in the treatment of penn class 3 and 4 cytokine release syndrome complicating COVID-19.

2020-11-0730 citations