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Tetrahydrobiopterin

DRUG6 trials

Sponsors

Emory University, University of Massachusetts, Worcester, University of Massachusetts, Amherst, West China Second University Hospital

Conditions

Alzheimer's DiseaseCOPDHypertensionKidney Failure, ChronicOxidative StressRadiation EnteritisRadiation-Induced DermatitisTetrahydrobiopterin Deficiency

Early Phase 1

Effects of Tetrahydrobiopterin on Blood Pressure
CompletedNCT00208780
Emory UniversityHypertension
Start: 2004-12-31End: 2005-12-31Updated: 2013-11-18

Phase 1

O2 Transport and Utilization in Health and Lung Disease
WithdrawnNCT04014712
University of Massachusetts, AmherstCOPD, Oxidative Stress, Tetrahydrobiopterin Deficiency
Start: 2021-04-30End: 2022-08-31Updated: 2023-12-19
A Study for Assessing the Efficacy and Safety of Tetrahydrobiopterin in Radiation-Induced Skin Injury
NCT05114226
West China Second University HospitalRadiation-Induced Dermatitis
Start: 2022-03-01End: 2024-01-01Target: 45Updated: 2022-02-28

Phase 2

Exercise Intolerance in Renal Failure
CompletedNCT01356966
Emory UniversityKidney Failure, Chronic
Start: 2011-05-31End: 2014-05-31Updated: 2015-06-01
Endothelial Facilitation in Alzheimer's Disease
CompletedNCT01439555
University of Massachusetts, WorcesterAlzheimer's Disease
Start: 2011-11-30End: 2017-11-30Updated: 2019-07-30
A Study for Assessing the Efficacy and Safety of BH4 in Radiation Enteritis
NCT05138887
West China Second University HospitalRadiation Enteritis
Start: 2022-03-01End: 2024-03-01Target: 366Updated: 2022-03-02

Related Papers

Cumulative effect of simvastatin, L-arginine, and tetrahydrobiopterin on cerebral blood flow and cognitive function in Alzheimer's disease.
2022-09-179 citations