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Tapinarof

DRUG7 trials

Sponsors

Organon and Co, Wake Forest University Health Sciences, Psoriasis Treatment Center of Central New Jersey, Indiana University, Northwestern University

Conditions

Atopic DermatitisCutaneous Lupus ErythematosusICD10 Code L40.9 for PsoriasisPalmoplantar KeratodermaPlaque PsoriasisPsoriasis

Early Phase 1

Tapinarof for Cutaneous Lupus Erythematosus
Enrolling by invitationNCT06661213
Northwestern UniversityCutaneous Lupus Erythematosus
Start: 2025-04-03End: 2026-03-31Target: 10Updated: 2025-05-07

Phase 2

Comparison of Post-Inflammatory Pigment Alteration After Psoriasis Treatment (PIPA - Dermavant)
Enrolling by invitationNCT05981118
Wake Forest University Health SciencesICD10 Code L40.9 for Psoriasis
Start: 2024-07-15End: 2026-12-31Target: 40Updated: 2025-12-17
Study to Evaluate the Safety and Efficacy of Tapinarof in Adults With Palmoplantar Keratoderma
RecruitingNCT06561321
Indiana UniversityPalmoplantar Keratoderma
Start: 2024-10-30End: 2027-12-31Target: 6Updated: 2026-03-04

Phase 3

Tapinarof for the Treatment of Plaque Psoriasis in Adults (3001)
CompletedNCT03956355
Organon and CoPlaque Psoriasis
Start: 2019-05-21End: 2020-05-26Updated: 2025-06-12
Tapinarof for the Treatment of Plaque Psoriasis in Adults (3002)
CompletedNCT03983980
Organon and CoPlaque Psoriasis
Start: 2019-06-06End: 2020-05-29Updated: 2025-06-12

Phase 4

Vtama in Psoriasis Patients Being Treated With Biologics.
CompletedNCT06103695
Psoriasis Treatment Center of Central New JerseyPsoriasis
Start: 2023-02-27End: 2023-10-18Updated: 2023-10-27
Utilization of a Microdevice for Psoriasis and Atopic Dermatitis
Not yet recruitingNCT07352566
University of California, San FranciscoAtopic Dermatitis, Psoriasis
Start: 2026-01-01End: 2030-06-01Target: 10Updated: 2026-01-20

Related Papers

Characteristics and management of follicular events and contact dermatitis in patients using tapinarof cream for the treatment of atopic dermatitis or plaque psoriasis.
2025-07-02
Rapid Improvements in Itch with Tapinarof Cream 1% Once Daily in Two Phase 3 Trials in Adults with Mild to Severe Plaque Psoriasis
Dermatology and Therapy2023-12-216 citations
Tapinarof cream 1% once daily for the treatment of adults with mild to severe plaque psoriasis: A novel topical therapy targeting the aryl hydrocarbon receptor.
2023-12-012 citations
Tapinarof Cream 1% Once Daily for the Treatment of Plaque Psoriasis: Case Photography of Clinical Outcomes from Three Phase 3 Trials
Dermatology and Therapy2023-09-118 citations
Rapid Improvements in Itch with Tapinarof Cream 1% Once Daily in Two Phase 3 Trials in Adults with Mild to Severe Plaque Psoriasis
SKIN The Journal of Cutaneous Medicine2023-03-132 citations
Psoriasis: Weitere kortikoidfreie topische Therapie in Sicht
Kompass Autoimmun2023-01-01
Psoriasis: Weitere kortikoidfreie topische Therapie in Sicht
Kompass Dermatologie2022-01-01
Phase 3 Trials of Tapinarof Cream for Plaque Psoriasis
New England Journal of Medicine2021-12-08164 citations