Tagraxofusp
Sponsors
Stemline Therapeutics, Inc., Gruppo Italiano Malattie EMatologiche dell'Adulto, Karen Ballen, MD, Joshua Zeidner, Therapeutic Advances in Childhood Leukemia Consortium
Conditions
ALLAMLAcute Myeloid Leukaemia (AML)Acute Myeloid LeukemiaAcute Myeloid Leukemia (AML)Acute Undifferentiated LeukemiaBPDCNBlastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)
Early Phase 1
Phase 1
Tagraxofusp in Patients With Blastic Plasmacytoid Dendritic Cell Neoplasm or Acute Myeloid Leukemia
CompletedNCT02113982
Start: 2014-09-30End: 2020-03-12Updated: 2024-08-01
Study of Tagraxofusp for Post-Transplant Maintenance for Patients With CD 123+ AML, MDS, MF and CMML (HSCT 002)
RecruitingNCT05233618
Start: 2022-07-13End: 2026-10-01Target: 44Updated: 2025-05-28
Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies
RecruitingNCT05476770
Start: 2022-11-11End: 2027-11-11Target: 54Updated: 2024-12-06
Tagraxofusp and Low-Intensity Chemotherapy for CD123-Positive Relapsed or Refractory AML
RecruitingNCT06561152
Start: 2025-02-10End: 2028-10-31Target: 20Updated: 2025-03-17
A Multi-Site Break Through Cancer Trial: Targeting Measurable Residual Disease in Patients With Acute Myeloid Leukemia: A Phase 1/2 Study of Tagraxofusp, Azacitidine, and Venetoclax
RecruitingNCT07148180
Start: 2026-02-02End: 2030-12-31Target: 31Updated: 2026-02-05
Phase 2
Tagraxofusp in Patients With CD123+ or With BPDCN-IPh-like Acute Myeloid Leukemia
TerminatedNCT04342962
Start: 2021-02-16End: 2024-01-18Updated: 2025-01-30
Tagraxofusp and Azacitidine With Venetoclax in Newly Diagnosed Secondary AML After Hypomethylating Agents
RecruitingNCT05442216
Start: 2024-05-01End: 2027-12-01Target: 53Updated: 2026-01-23
A Study of Tagraxofusp in Combination With Venetoclax and Azacitidine in Adults With Untreated CD123+ Acute Myeloid Leukemia Who Cannot Undergo Intensive Chemotherapy
RecruitingNCT06456463
Start: 2025-01-14End: 2030-02-11Target: 83Updated: 2026-03-09
Phase II Study Evaluating the Efficacy and Safety of the Combination of Tagraxofusp and Venetoclax in Treatment-naive Blastic Plasmacytoid Dendritic Cell Neoplasm Patients
Not yet recruitingNCT07007052
Start: 2025-12-01End: 2031-09-30Target: 33Updated: 2025-11-26
Related Papers
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