Tadalafil 20 MG

DRUG11 trials

Sponsors

Rambam Health Care Campus, Cedars-Sinai Medical Center, Insel Gruppe AG, University Hospital Bern, Centro Universitario de Ciencias de la Salud, Mexico, Federico II University

Conditions

Cerebral Small Vessel DiseasesErectile DysfunctionErectile Dysfunction Following Radical ProstatectomyGastric AdenocarcinomaGastroesophageal Junction AdenocarcinomaHealthyHeart Defects, CongenitalMuscular Dystrophy

Early Phase 1

The Study of Skeletal Muscle Blood Flow in Becker Muscular Dystrophy

TerminatedNCT02653833

Cedars-Sinai Medical CenterMuscular Dystrophy

Start: 2017-11-01End: 2018-09-01Updated: 2020-01-14

Phase 1

A Study of Macitentan/Tadalafil Combination Administered a Fixed-dose Combination Formulation Compared to the Reference Free Combination of Macitentan and Tadalafil

CompletedNCT04540744

Janssen Research & Development, LLCHealthy

Start: 2021-04-30End: 2021-08-30Updated: 2025-03-30

A Study of Fixed Dose Combination of Macitentan/Tadalafil (10 mg/20 mg) Compared to the Reference Free Combination of Macitentan and Tadalafil in Healthy Adult Participants

CompletedNCT05236231

ActelionHealthy

Start: 2022-02-04End: 2022-05-14Updated: 2025-03-30

Phase 2

Effect of PDE5 Inhibition on Adipose Metabolism in Humans

CompletedNCT04684589

Vanderbilt University Medical CenterObesity

Start: 2021-03-16End: 2025-06-24Updated: 2025-08-29

Improving Cerebral Blood Flow and Cognition in Patients with Cerebral Small Vessel Disease. the ETLAS-2 Trial

Active, not recruitingNCT05173896

Christina KruuseCerebral Small Vessel Diseases, Stroke, Ischemic

Start: 2022-05-31End: 2029-12-31Target: 100Updated: 2024-12-09

Tadalafil Effect + Chemotherapy in Resectable Gastric/GEJ Cancer

RecruitingNCT05709574

University of ArizonaGastric Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma

Start: 2023-04-20End: 2026-05-31Target: 10Updated: 2025-10-16

Phase 3

Effect of Phosphodiesterase-5 Inhibition With Tadalafil on SystEmic Right VEntricular Size and Function

CompletedNCT03049540

Insel Gruppe AG, University Hospital BernHeart Defects, Congenital, Transposition of Great Vessels With Ventricular Inversion

Start: 2017-10-25End: 2021-10-28Updated: 2023-06-23

Effect of Tadalafil Administration on Vasodilatation Mediated by Flow in Patients With Obesity Grade I-II

Centro Universitario de Ciencias de la Salud, MexicoObesity and Erectile Dysfuntion

Start: 2019-05-01End: 2019-09-01Target: 80Updated: 2019-04-05

Phase 4

Evaluation of Safety and Effectiveness of 2 Lower Dose Combined PDE5i's Versus Single Maximal Dose PDE5i Treatment

Rambam Health Care CampusErectile Dysfunction

Start: 2011-06-30End: 2012-07-31Target: 30Updated: 2011-06-20

Unknown Phase

Study of Retinal and Choriocapillary Vascular Changes in Patients Undergoing Tadalafil 20mg

CompletedNCT04164355

Federico II UniversityErectile Dysfunction Following Radical Prostatectomy

Start: 2020-07-04End: 2021-04-30Updated: 2021-09-24

Study of Retinal and Choriocapillary Vascular Changes in Patients Undergoing Tadalafil 20mg for More Than 6 Months

CompletedNCT04491773

Federico II UniversityErectile Dysfunction Following Radical Prostatectomy

Start: 2019-11-01End: 2020-05-30Updated: 2020-07-29

Related Papers

Cognitive outcomes after tadalafil treatment in patients with cerebral small vessel disease: ETLAS-2 sub-study.

2025-11-11

Tadalafil Treatment in Patients With Cerebral Small Vessel Disease: The ETLAS-2 Randomized Clinical Trial

Stroke2025-07-281 citations

Stable Longitudinal Quality of Life in the SERVE Trial Among Adults With Transposition of the Great Arteries and a Systemic Right Ventricle

CJC Pediatric and Congenital Heart Disease2024-12-122 citations

Cerebral blood flow and cognition after 3 months tadalafil treatment in small vessel disease (ETLAS-2): study protocol for a randomized controlled trial

Trials2024-08-292 citations

Modifying the gastric tumor microenvironment with tadalafil: A transcriptomic analysis of immune signatures from underserved patients of southern Arizona.

Journal of Clinical Oncology2024-06-01

Prognostic Value and Determinants of High‐Sensitivity Cardiac Troponin T in Patients With a Systemic Right Ventricle: Insights From the SERVE Trial

Journal of the American Heart Association2024-05-103 citations

Effect of Phosphodiesterase-5 Inhibition on Systemic Right Ventricular Size and Function. A Multicentre, Double-Blind, Randomized, Placebo-Controlled Trial: SERVE

European Journal of Heart Failure2023-06-0213 citations

Tadalafil Improves Haemodynamics and Arterial Stiffness but Not Flow-Mediated Dilation in Grade 1 Obesity. A Single-dose, Placebo-controlledClinical Trial

Current Vascular Pharmacology2022-08-301 citations