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Sulfamethoxazole-Trimethoprim

DRUG16 trials

Sponsors

National Institute of Allergy and Infectious Diseases (NIAID), Bandim Health Project, UMC Utrecht, Shilpa Grover, MD, MPH

Conditions

Bacterial InfectionsChronic Otitis MediaHIV InfectionsImmune Checkpoint Inhibitor-Related ColitisMeaslesMycosesPneumonia, Pneumocystis CariniiPost-Measles Pneumonia

Phase 1

Effect of Fluconazole, Clarithromycin, and Rifabutin on the Pharmacokinetics of Sulfamethoxazole-Trimethoprim and Dapsone and Their Hydroxylamine Metabolites
CompletedNCT00000826
National Institute of Allergy and Infectious Diseases (NIAID)Bacterial Infections, HIV Infections, Mycoses
End: 1999-05-31Target: 48Updated: 2021-10-29

Phase 2

A Randomized, Double-Blind Study of 566C80 Versus Septra (Sulfamethoxazole/Trimethoprim) for the Treatment of Pneumocystis Carinii Pneumonia in AIDS Patients
CompletedNCT00000655
National Institute of Allergy and Infectious Diseases (NIAID)HIV Infections, Pneumonia, Pneumocystis Carinii
Target: 300Updated: 2011-03-01
A Study to Compare Different Drugs Used to Prevent Serious Bacterial Infections in HIV-Positive Children
CompletedNCT00000811
National Institute of Allergy and Infectious Diseases (NIAID)Bacterial Infections, HIV Infections, Pneumonia, Pneumocystis Carinii
End: 2001-11-30Target: 690Updated: 2021-11-04
Early Vedolizumab as First-Line for Immune-Related Colitis Therapy Trial
RecruitingNCT06841705
Shilpa Grover, MD, MPHImmune Checkpoint Inhibitor-Related Colitis
Start: 2025-07-15End: 2026-12-31Target: 80Updated: 2025-11-04

Phase 3

A Randomized, Comparative, Prospective Study of Daily Trimethoprim / Sulfamethoxazole (TMS) and Thrice-Weekly TMS for Prophylaxis Against PCP in HIV-Infected Patients
CompletedNCT00000748
National Institute of Allergy and Infectious Diseases (NIAID)HIV Infections, Pneumonia, Pneumocystis Carinii
End: 1996-11-30Target: 2500Updated: 2021-11-04
Comparison of Trimetrexate Plus Leucovorin Calcium Rescue Versus Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS
CompletedNCT00001013
National Institute of Allergy and Infectious Diseases (NIAID)HIV Infections, Pneumonia, Pneumocystis Carinii
End: 1991-09-30Target: 364Updated: 2021-11-04
A Phase III Comparative Study of Dapsone / Trimethoprim and Clindamycin / Primaquine Versus Sulfamethoxazole / Trimethoprim in the Treatment of Mild-to-Moderate PCP in Patients With AIDS
CompletedNCT00000640
National Institute of Allergy and Infectious Diseases (NIAID)HIV Infections, Pneumonia, Pneumocystis Carinii
End: 1994-09-30Target: 290Updated: 2021-11-03
A Controlled Trial Comparing the Efficacy of Aerosolized Pentamidine and Parenteral/Oral Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia in AIDS
CompletedNCT00000715
National Institute of Allergy and Infectious Diseases (NIAID)HIV Infections, Pneumonia, Pneumocystis Carinii
End: 1991-09-30Target: 240Updated: 2021-11-03
A Study of Three Drugs Plus Zidovudine in the Prevention of Infections in HIV-Infected Patients
CompletedNCT00000991
National Institute of Allergy and Infectious Diseases (NIAID)HIV Infections, Pneumonia, Pneumocystis Carinii
End: 1994-04-30Target: 600Updated: 2021-11-04
Comparison of Three Treatments for Pneumocystis Pneumonia in AIDS Patients
TerminatedNCT00000730
National Institute of Allergy and Infectious Diseases (NIAID)HIV Infections, Pneumonia, Pneumocystis Carinii
End: 1989-03-31Target: 240Updated: 2021-11-03
Trimetrexate Plus Leucovorin Calcium Rescue Versus Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS
CompletedNCT00001014
National Institute of Allergy and Infectious Diseases (NIAID)HIV Infections, Pneumonia, Pneumocystis Carinii
End: 1991-09-30Target: 302Updated: 2021-11-04
Prophylactic Antibiotics in Measles
CompletedNCT00168532
Bandim Health ProjectMeasles, Post-Measles Pneumonia
Start: 1998-01-31End: 2001-10-31Target: 218Updated: 2008-02-26

Phase 4

Gradual Initiation of Sulfamethoxazole/Trimethoprim as Primary Pneumocystis Carinii Pneumonia Prophylaxis
CompletedNCT00000816
National Institute of Allergy and Infectious Diseases (NIAID)HIV Infections, Pneumonia, Pneumocystis Carinii
End: 1996-09-30Target: 370Updated: 2021-11-04

Unknown Phase

Evaluation of the Interaction Between High Dose Sulfamethoxazole/Trimethoprim and Zidovudine
CompletedNCT00000734
National Institute of Allergy and Infectious Diseases (NIAID)HIV Infections
End: 1990-05-31Target: 10Updated: 2021-10-28
Evaluation of the Interaction Between Low Dose Sulfamethoxazole-Trimethoprim and Zidovudine
CompletedNCT00000732
National Institute of Allergy and Infectious Diseases (NIAID)HIV Infections
End: 1990-05-31Target: 10Updated: 2021-11-03
Effectiveness of Sulfamethoxazole-trimethoprim in the Treatment of Chronic Otitis Media
CompletedNCT00189098
UMC UtrechtChronic Otitis Media
Start: 2003-02-28End: 2006-11-30Updated: 2012-07-13

Related Papers

Effect of long-term trimethoprim/sulfamethoxazole treatment on resistance and integron prevalence in the intestinal flora: a randomized, double-blind, placebo-controlled trial in children.
2009-03-1825 citations