Sugammadex 4 mg/kg

DRUG8 trials

Conditions

AnesthesiaHypersensitivityMorbid ObesityNeuromuscular BlockadeProstate CancerReversal of Neuromuscular BlockadeSurgical Procedure, Unspecified

Phase 1

Sugammadex Hypersensitivity Study (Study P06042)

CompletedNCT00988065

Merck Sharp & Dohme LLCHypersensitivity

Start: 2009-09-06End: 2010-04-13Updated: 2019-01-30

Phase 2

Sugammadex Dosage Based on Ideal Body Weight for Profound Rocuronium-induced Neuromuscular Blockade Reversal in Morbidly Obese Patients

CompletedNCT02545595

Poitiers University HospitalMorbid Obesity

Start: 2012-05-31Updated: 2016-10-12

Phase 3

Dose-Finding Pediatric and Adult Trial With Sugammadex (Org 25969, MK-8616, SCH 900616) (19.4.306) (MK-8616-034) (P05961)

CompletedNCT00421148

Merck Sharp & Dohme LLCAnesthesia

Start: 2005-05-30End: 2006-06-02Updated: 2019-01-28

Recovery From dNMB Using Different Sugammadex Doses in Elderly Patients Undergoing Robot-assisted Prostatectomy

CompletedNCT04854993

Fondazione Policlinico Universitario Agostino Gemelli IRCCSNeuromuscular Blockade, Prostate Cancer

Start: 2021-07-13End: 2022-09-23Updated: 2023-01-25

Phase 4

Safety of Sugammadex for the Reversal of Neuromuscular Blockade in American Society of Anesthesiologists (ASA) Class 3 or 4 Participants (MK-8616-145)

CompletedNCT03346057

Merck Sharp & Dohme LLCReversal of Neuromuscular Blockade

Start: 2017-12-20End: 2019-09-04Updated: 2020-10-08

Efficacy, Safety, and Pharmacokinetics of Sugammadex for Reversal of Neuromuscular Blockade (NMB) in Pediatric Participants (MK-8616-089)

CompletedNCT03351608

Merck Sharp & Dohme LLCNeuromuscular Blockade

Start: 2018-02-12End: 2020-01-28Updated: 2021-02-05

Efficacy, Safety, and Pharmacokinetics of Sugammadex (MK-8616) for Reversal of Neuromuscular Blockade in Pediatric Participants Aged Birth to <2 Years (MK-8616-169)

CompletedNCT03909165

Merck Sharp & Dohme LLCNeuromuscular Blockade

Start: 2019-07-23End: 2023-09-21Updated: 2025-07-25

Unknown Phase

Sugammadex: Effect on the Awareness Monitoring and Hemodynamics

NCT01301261

University of AthensSurgical Procedure, Unspecified

Start: 2010-12-31Target: 60Updated: 2012-06-19

Related Papers

Sugammadex for Reversal of Neuromuscular Blockade in Neonates and Infants Less than 2 Years Old: Results from a Phase IV Randomized Clinical Trial

Anesthesiology2025-05-055 citations

Sugammadex for reversal of neuromuscular blockade in pediatric patients: Results from a phase IV randomized study

Pediatric Anesthesia2021-12-0822 citations

A randomized trial evaluating the safety profile of sugammadex in high surgical risk ASA physical class 3 or 4 participants

BMC Anesthesiology2021-10-2814 citations

Sugammadex hypersensitivity and underlying mechanisms: a randomised study of healthy non-anaesthetised volunteers.

2018-07-1339 citations