Standard of Care (Investigator Choice)

OTHER13 trials

Sponsors

NewLink Genetics Corporation, Western University, Mayo Clinic, Advanced Reconstructive Surgery Alliance, Royal Biologics

Conditions

Abdominal Surgery PatientsAcute Decompensated Heart FailureAcute-on-Chronic Liver Failure (ACLF)Adenoid Cystic Carcinoma of the Head and NeckAdenoid Cystic Carcinoma of the Salivary GlandAmnio-MaxxAnxietyBreast Cancer

Phase 2

CRLX101(NLG207) in Combination With Bevacizumab for Metastatic Renal Cell Carcinoma (mRCC) Versus Standard of Care (SOC)

CompletedNCT02187302

NewLink Genetics CorporationMetastatic Renal Cell Carcinoma

Start: 2014-07-31End: 2017-01-31Updated: 2020-05-28

Phase 3

A Novel Extracorporeal Liver Support Therapy In ALCF and to Evaluate the Efficacy of DIALIVE 2.0, a Liver Dialysis Device.

Not yet recruitingNCT07347275

Yaqrit LtdAcute-on-Chronic Liver Failure (ACLF), Liver Cirrhosis

Start: 2026-02-01End: 2027-05-01Target: 72Updated: 2026-01-16

Phase 4

Effect of Amnio-Maxx on the Healing Rate of Chronic Diabetic Foot Ulcers.

RecruitingNCT07209475

Royal BiologicsAmnio-Maxx, Diabetic Foot Ulcer (DFU)

Start: 2025-08-14End: 2026-08-14Target: 248Updated: 2025-10-07

Pivmecillinam as Oral Step-Down Treatment for Escherichia Coli Febrile Urinary Tract Infection Versus Standard of Care

RecruitingNCT07236944

Uppsala UniversityFebrile Urinary Tract Infection

Start: 2025-12-31End: 2029-03-31Target: 560Updated: 2025-12-17

Adjunctive Hyperbaric Oxygen Treatment for Patients With Necrotizing Soft-Tissue Infection (HOT-NSTI Trial).

Not yet recruitingNCT07489274

Ole HyldegaardNecrotizing Soft Tissue Infection

Start: 2026-04-01End: 2033-06-30Target: 1480Updated: 2026-03-30

Unknown Phase

WECARE APD: Assessing a Single Multidisciplinary Team Visit for Atypical Parkinsonian Disorders

Not yet recruitingNCT06836921

Western UniversityParkinson Plus

Start: 2025-03-15End: 2026-07-20Target: 30Updated: 2025-02-20

Evaluation of a Novel Drain Stripping Device for Reducing Surgical Drain Complications

Enrolling by invitationNCT07119112

Mayo ClinicAbdominal Surgery Patients, Drains, Surgical Drain

Start: 2026-02-20End: 2027-01-01Target: 500Updated: 2026-02-24

Targeted Nerve Surgery for the Prevention of Post-Mastectomy Pain Syndrome: A Randomized Trial

Not yet recruitingNCT07146009

Advanced Reconstructive Surgery AllianceBreast Cancer

Start: 2025-10-31End: 2028-02-25Target: 60Updated: 2025-08-28

PREcision meDICine in Treatment in CardioVascular Disease

Not yet recruitingNCT07369141

Maastricht University Medical CenterAcute Decompensated Heart Failure, Chronic Heart Failure

Start: 2026-02-01End: 2028-06-01Target: 430Updated: 2026-01-27

OEOd-Based Wound Dressing in Post-Surgical Diabetic Foot Ulcers

CompletedNCT07368816

Ospedale San DonatoDiabetic Foot, Postoperative Wound Healing

Start: 2024-03-01End: 2025-04-30Updated: 2026-01-27

Effectiveness and Safety of a Type A Dissection Total Endovascular Reconstruction System in Promoting Favorable Distal Aortic Remodeling

Not yet recruitingNCT07402252

West China HospitalResidual Dissection After Repair for Type A Aortic Dissection

Start: 2026-02-09End: 2031-12-31Target: 198Updated: 2026-02-11

Sleep Well Firefighters: An App-based Program to Improve Sleep, Cognition, and Behavioral Health in Firefighters

RecruitingNCT07477184

California Polytechnic State University-San Luis ObispoAnxiety, Cognition, Nutrition +3

Start: 2026-01-05End: 2026-09-01Target: 50Updated: 2026-03-17

A Multi-omics Approach to Disclose Progression and Underlying Biology of Head and Neck Adenoid Cystic Carcinoma

RecruitingNCT07507578

Fondazione IRCCS Istituto Nazionale dei Tumori, MilanoAdenoid Cystic Carcinoma of the Head and Neck, Adenoid Cystic Carcinoma of the Salivary Gland

Start: 2025-03-01End: 2028-12-31Target: 114Updated: 2026-04-02

Related Papers

A randomized phase II trial of CRLX101 in combination with bevacizumab versus standard of care in patients with advanced renal cell carcinoma

Annals of Oncology2017-09-0976 citations

Randomized phase 2 study to assess the safety and efficacy of CRLX101 in combination with bevacizumab in patients (pts.) with metastatic renal cell carcinoma (RCC) versus standard of care (SOC).

Journal of Clinical Oncology2015-05-204 citations