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somapacitan

DRUG20 trials

Sponsors

Novo Nordisk A/S

Conditions

Adult Growth Hormone DeficiencyDiabetes Mellitus Type 2Growth Hormone DeficiencyGrowth Hormone Deficiency in ChildrenGrowth Hormone DisorderHealthyHealthy VolunteersISS

Phase 1

First Human Dose Trial of NNC0195-0092 (Somapacitan) in Healthy Subjects
CompletedNCT01514500
Novo Nordisk A/SAdult Growth Hormone Deficiency, Growth Hormone Deficiency in Children, Growth Hormone Disorder +1
Start: 2012-01-16End: 2013-03-18Updated: 2020-12-24
A Trial Investigating the Safety, Tolerability, Availability and Distribution in the Body of Once-weekly Long-acting Growth Hormone (Somapacitan) Compared to Once Daily Norditropin NordiFlex® in Adults With Growth Hormone Deficiency
CompletedNCT01706783
Novo Nordisk A/SAdult Growth Hormone Deficiency, Growth Hormone Disorder
Start: 2012-10-12End: 2013-11-18Updated: 2020-12-24
A Trial Investigating Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of a Single Dose of Long-acting Growth Hormone (Somapacitan) Compared to Daily Dosing of Norditropin® SimpleXx® in Children With Growth Hormone Deficiency
CompletedNCT01973244
Novo Nordisk A/SGrowth Hormone Deficiency in Children, Growth Hormone Disorder
Start: 2013-12-16End: 2014-11-04Updated: 2020-12-24
A Trial Investigating the Absorption, Metabolism and Excretion of Somapacitan After Single Dosing in Healthy Male Subjects
CompletedNCT02962440
Novo Nordisk A/SHealthy
Start: 2016-11-30End: 2017-01-31Updated: 2017-06-07
Investigation of Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Multiple Doses of Somapacitan in Subjects With Various Degrees of Impaired Renal Function Compared to Subjects With Normal Renal Function
CompletedNCT03186495
Novo Nordisk A/SAdult Growth Hormone Deficiency, Growth Hormone Deficiency in Children, Growth Hormone Disorder
Start: 2017-06-20End: 2018-05-17Updated: 2020-04-17
Investigation of Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Multiple Doses of Somapacitan in Subjects With Mild and Moderate Degrees of Hepatic Impairment Compared to Subjects With Normal Hepatic Function.
CompletedNCT03212131
Novo Nordisk A/SAdult Growth Hormone Deficiency, Growth Hormone Deficiency in Children, Growth Hormone Disorder
Start: 2017-08-16End: 2018-03-08Updated: 2019-05-24
A Study to Compare the Uptake Into the Blood of Two Strengths of Somapacitan After Injection Under the Skin in Healthy Subjects
CompletedNCT03905850
Novo Nordisk A/SGrowth Hormone Deficiency, Healthy Volunteers
Start: 2019-03-29End: 2019-07-15Updated: 2019-08-06

Phase 2

Phase 3

Trial to Compare the Efficacy and Safety of NNC0195-0092 (Somapacitan) With Placebo and Norditropin® FlexPro® (Somatropin) in Adults With Growth Hormone Deficiency.
CompletedNCT02229851
Novo Nordisk A/SAdult Growth Hormone Deficiency, Growth Hormone Disorder
Start: 2014-10-31End: 2018-05-07Updated: 2020-11-23
A Trial to Compare the Safety of Once Weekly Dosing of Somapacitan With Daily Norditropin® FlexPro® for 26 Weeks in Previously Human Growth Hormone Treated Adults With Growth Hormone Deficiency
CompletedNCT02382939
Novo Nordisk A/SAdult Growth Hormone Deficiency, Growth Hormone Disorder
Start: 2015-02-12End: 2016-01-04Updated: 2020-07-09
A Trial to Evaluate the Safety of Once Weekly Dosing of Somapacitan (NNC0195-0092) and Daily Norditropin® FlexPro® for 52 Weeks in Previously Human Growth Hormone Treated Japanese Adults With Growth Hormone Deficiency
CompletedNCT03075644
Novo Nordisk A/SAdult Growth Hormone Deficiency, Growth Hormone Disorder
Start: 2017-03-03End: 2018-10-04Updated: 2020-11-23
A Research Study in Children With a Low Level of Hormone to Grow. Treatment is Somapacitan Once a Week Compared to Norditropin® Once a Day (REAL4)
CompletedNCT03811535
Novo Nordisk A/SGrowth Hormone Deficiency in Children
Start: 2019-05-20End: 2025-09-30Updated: 2026-05-22
A Research Study in Chinese Children With a Low Level of Hormone to Grow. Treatment is Somapacitan Once a Week Compared to Norditropin® Once a Day.
CompletedNCT04970654
Novo Nordisk A/SGrowth Hormone Deficiency in Children
Start: 2021-07-22End: 2023-12-18Updated: 2026-01-06
A Research Study to Compare Somapacitan Once a Week With Norditropin® Once a Day in Children Who Need Help to Grow
Active, not recruitingNCT05330325
Novo Nordisk A/SSGA, Turner Syndrome, Noonan Syndrome, ISS
Start: 2022-08-10End: 2027-10-29Updated: 2026-06-12
A Research Study Looking at How Safe Somapacitan is and How Well it Works in Children Who Need Help to Grow - REAL 9
Active, not recruitingNCT05723835
Novo Nordisk A/SISS, Noonan Syndrome, SGA +1
Start: 2023-02-01End: 2027-10-29Updated: 2026-08-13

Unknown Phase

Related Papers

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