Solu-Cortef Powder for Solution for Injection or Infusion 100 mg
Sponsors
Allogene Therapeutics Inc., Princess Maxima Center For Pediatric Oncology, Royal College Of Surgeons In Ireland, Prinses Maxima Centrum voor Kinderoncologie B.V.
Conditions
Acute Lymphocytic LeukemiaAcute Myeloid LeukemiaAcute lymphoblastic leukemiaAddison’s DiseaseLarge B-Cell Lymphoma (LBCL)Mixed Phenotype Acute Leukemia
Phase 1
Phase 2
An open-label, cross-over, multi-site, prospective, phase IIb study of effects on circadian rhythms and quality of life of modifieddual-release hydrocortisone Efmody™ versus immediate-release hydrocortisone in patients with Addison’s Disease
CompletedCTIS2023-503584-42-00
Start: 2023-12-22End: 2024-09-09Target: 30Updated: 2024-08-07
A Single-Arm, Open-Label, Phase 1/2 Study Evaluating the Safety, Efficacy, and Cellular Kinetics/Pharmacodynamics of ALLO-501A, an Anti-CD19 Allogeneic CAR T Cell Therapy, and ALLO-647, an Anti-CD52 Monoclonal Antibody, in Subjects with Relapsed/Refractory Large B Cell Lymphoma (LBCL).
CompletedCTIS2022-501927-25-00
Start: 2023-09-29End: 2024-01-12Target: 35Updated: 2024-01-15
A Randomized, Open-Label, Phase 2 Study Evaluating Lymphodepletion With Fludarabine, Cyclophosphamide, And ALLO-647, Vs. Fludarabine And Cyclophosphamide Alone, In Subjects With Relapsed/Refractory Large B-Cell Lymphoma (LBCL) Receiving ALLO-501A Allogeneic CAR T Cell Therapy
CompletedCTIS2023-503830-27-00
Start: 2023-10-17End: 2024-10-28Target: 35Updated: 2024-01-29
Phase 3
Interfant-21: International collaborative treatment protocol for infants under one year with KMT2A-rearranged acute lymphoblastic leukemia or mixed phenotype acute leukemia
SuspendedCTIS2022-502503-30-00
Start: 2022-12-15Target: 206Updated: 2026-01-27
CHIP-AML22 Master protocol: An open label complex clinical trial in newly diagnosed pediatric de novo AML patients – a study by the NOPHO-DB-SHIP consortium Master Protocol
RecruitingCTIS2023-504999-25-00
Start: 2023-07-14Target: 675Updated: 2025-08-14