SIR-Spheres microspheres

DEVICE4 trials

Sponsors

Sirtex Medical, Emory University

Conditions

CancerCancer of LiverCarcinoma, HepatocellularColorectal Cancer MetastaticColorectal CarcinomaHCCHepatomaLiver Metastases

Phase 2

FOLFOX6 Plus Sir-Spheres Microspheres Plus Avastin in Patients With Nonresectable Liver Metastases From Colorectal Carcinoma

WithdrawnNCT00735241

Sirtex MedicalColorectal Carcinoma, Liver Metastases

Start: 2008-07-31End: 2009-03-31Updated: 2015-05-22

Phase 3

FOLFOX6m Plus SIR-Spheres Microspheres vs FOLFOX6m Alone in Patients With Liver Mets From Primary Colorectal Cancer

CompletedNCT01721954

Sirtex MedicalColorectal Cancer Metastatic

Start: 2013-05-01End: 2017-02-28Updated: 2019-11-05

Unknown Phase

SIR-Spheres® for the Treatment of Unresectable Hepatocellular Carcinoma

TerminatedNCT00503867

Sirtex MedicalCarcinoma, Hepatocellular, Hepatoma

Start: 2007-07-18End: 2010-03-09Updated: 2020-12-10

Low-dose Y90 Treatment Planning for HCC

CompletedNCT04172714

Emory UniversityCancer, Cancer of Liver, HCC

Start: 2019-12-16End: 2021-06-30Updated: 2022-12-06

Related Papers

Resin-Based 90Y Tumor Dose as a Predictor of Duration of Response and Survival in Patients With Surgically Unresectable Hepatocellular Carcinoma

Clinical Nuclear Medicine2024-05-218 citations

Voxel-based dosimetry predicting treatment response and related toxicity in HCC patients treated with resin-based Y90 radioembolization: a prospective, single-arm study

European Journal of Nuclear Medicine and Molecular Imaging2023-01-1742 citations

Accuracy and Safety of Scout Dose Resin Yttrium-90 Microspheres for Radioembolization Therapy Treatment Planning: A Prospective Single-Arm Clinical Trial.

2022-09-0618 citations

Quality of life in the FOXFIRE, SIRFLOX and FOXFIRE‐global randomised trials of selective internal radiotherapy for metastatic colorectal cancer

International Journal of Cancer2019-12-1614 citations

First-line selective internal radiotherapy plus chemotherapy versus chemotherapy alone in patients with liver metastases from colorectal cancer (FOXFIRE, SIRFLOX, and FOXFIRE-Global): a combined analysis of three multicentre, randomised, phase 3 trials.

2017-08-03224 citations

Protocol for Combined Analysis of FOXFIRE, SIRFLOX, and FOXFIRE-Global Randomized Phase III Trials of Chemotherapy +/- Selective Internal Radiation Therapy as First-Line Treatment for Patients With Metastatic Colorectal Cancer

JMIR Research Protocols2017-03-2822 citations