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Sham vagus nerve stimulation

DEVICE10 trials

Sponsors

Northwell Health, Xidian University, Xijing Hospital, Aalborg University Hospital, Rigshospitalet, Denmark

Conditions

Acute Postoperative PainAlzheimer Disease (AD)Autonomic DysfunctionAutonomic NeuropathyCIPNChemotherapy-induced Peripheral NeuropathyDepressionDiabetes Mellitus

Phase 2

Transcutaneous Vagus Nerve Stimulation in SLE
RecruitingNCT06987565
Northwell HealthSystemic Lupus Erythematosus
Start: 2025-07-25End: 2027-09-01Target: 18Updated: 2026-09-17

Unknown Phase

Using the Cholinergic Anti-Inflammatory Pathway to Treat Systemic Lupus Musculoskeletal Pain
CompletedNCT02822989
Northwell HealthLupus Erythematosus, Systemic, Musculoskeletal Pain
Start: 2017-11-01End: 2020-11-01Updated: 2026-07-08
Using a Transcutaneous Electrical Auricular Stimulator to Harness the Cholinergic Anti-Inflammatory Pathway
CompletedNCT02910973
Northwell HealthHealthy Volunteers
Start: 2016-09-30End: 2023-12-13Updated: 2024-02-22
Neural Alteration Response to Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) in Depressed Patients
NCT03592446
Xidian UniversityDepression
Start: 2018-09-01End: 2020-07-30Target: 60Updated: 2018-07-19
Clinical Study of Escitalopram Oxalate Combined With taVNS in Depression and Concomitant Inflammatory Symptoms
NCT04037111
Xijing HospitalMajor Depressive Disorder, Rheumatoid Arthritis
Start: 2019-07-23End: 2021-12-31Target: 90Updated: 2019-08-20
Treatment of Complications to Diabetic Autonomic Neuropathy With Vagus Nerve Stimulation
CompletedNCT04143269
Aalborg University HospitalDiabetes Mellitus, Gastrointestinal Dysfunction
Start: 2020-01-20End: 2023-02-01Updated: 2023-06-07
Vagus Nerve Stimulation for Systemic Lupus Erythematous
CompletedNCT05315739
Rigshospitalet, DenmarkAutonomic Dysfunction, Autonomic Neuropathy, Fatigue +1
Start: 2022-08-24End: 2023-08-23Updated: 2025-09-26
Transauricular Vagus Nerve Stimulation in the Treatment of Chemotherapy-induced Peripheral Neuropathy
NCT05434403
Peking University People's HospitalChemotherapy-induced Peripheral Neuropathy, CIPN
Start: 2022-06-02End: 2022-11-01Target: 26Updated: 2022-06-28
Effects of tDCS and VNS on Postoperative Analgesia
Not yet recruitingNCT06554067
Columbia UniversityAcute Postoperative Pain
Start: 2024-08-31End: 2026-08-31Target: 200Updated: 2024-08-14
Alzheimer's Disease Treated With Vagus Nerve Stimulation
RecruitingNCT06923007
Beijing Municipal Administration of HospitalsAlzheimer Disease (AD)
Start: 2025-05-07End: 2027-12-31Target: 74Updated: 2025-06-06

Related Papers

Transcutaneous vagus nerve stimulation has no anti-inflammatory effect in diabetes
Scientific Reports2024-09-096 citations
Transcutaneous vagal nerve stimulation for treating gastrointestinal symptoms in individuals with diabetes: a randomised, double-blind, sham-controlled, multicentre trial.
2024-03-2810 citations
Effect of transcutaneous auricular vagal nerve stimulation on the fatigue syndrome in patients with gastrointestinal cancers - FATIVA: a randomized, placebo-controlled pilot study protocol.
2023-04-227 citations
Vagus nerve stimulation as a novel treatment for systemic lupus erythematous: study protocol for a randomised, parallel-group, sham-controlled investigator-initiated clinical trial, the SLE-VNS study
BMJ Open2022-09-0110 citations
Study protocol for a multicentre, randomised, parallel group, sham-controlled clinical trial investigating the effect of transcutaneous vagal nerve stimulation on gastrointestinal symptoms in people with diabetes complicated with diabetic autonomic neuropathy: the DAN-VNS Study
BMJ Open2021-01-0124 citations
Effects of Vagus Nerve Stimulation in a Murine Model of Systemic Lupus Erythematosus
The FASEB Journal2018-04-012 citations