Sham transcutaneous vagal nerve stimulation

DEVICE2 trials

Sponsors

Washington University School of Medicine

Conditions

Acute Ischemic StrokeLarge Vessel Occlusion

Unknown Phase

Neuromodulation Using Vagus Nerve Stimulation Following Ischemic Stroke as Therapeutic Adjunct

CompletedNCT05390580

Washington University School of MedicineAcute Ischemic Stroke

Start: 2022-09-26End: 2024-08-23Updated: 2025-10-31

Non-invasive Vagus Nerve Stimulation to Reduce Inflammation and Brain Injury Blood Biomarkers Following an Acute Ischemic Stroke

RecruitingNCT07404852

Washington University School of MedicineAcute Ischemic Stroke, Large Vessel Occlusion

Start: 2026-02-23End: 2028-02-29Target: 65Updated: 2026-04-13

Related Papers

Neurofilament light chain dynamics following ischemic stroke and their modulation by transauricular vagus nerve stimulation

Scientific Reports2026-08-31

Transcutaneous Auricular Vagus Nerve Stimulation Reduces Inflammatory Biomarkers after Large Vessel Occlusion Stroke: Results of a Prospective Randomized Open-Label Blinded Endpoint Trial.

2025-12-22