SGLT2i

DRUG8 trials

Conditions

Acute Decompensated Heart FailureCKD - Chronic Kidney DiseaseCardiac Allograft VasculopathyCardiologyCardiovascular DiseasesHeart Failure With Reduced Ejection FractionKidney Transplant RecipientNon-Diabetic Patients

Phase 2

Impact of SGLT2 Inhibitors in Heart Transplant Recipients

Enrolling by invitationNCT06147271

Universidade Federal do CearaCardiac Allograft Vasculopathy, Rejection Heart Transplant, Transplant; Failure, Heart

Start: 2023-11-20End: 2025-08-01Target: 80Updated: 2024-05-07

SGLT2i Effect on PTDM Development and Kidney Allograft Function in Non-diabetic Kidney Transplant Recipients: A Randomized, Doubleblind, Placebo Controlled, National Multicenter Trial

Not yet recruitingNCT07682350

Odense University HospitalKidney Transplant Recipient, Non-Diabetic Patients, Placebo Control Design +3

Start: 2026-09-01End: 2029-10-01Target: 184Updated: 2026-07-02

Phase 4

HF Patients With LVADs Being Treated With SGLT2i

CompletedNCT05278962

University of ChicagoHeart Failure With Reduced Ejection Fraction

Start: 2022-09-08End: 2025-08-31Updated: 2026-06-03

The Hemodynamic Effects of SGLT2i in Acute Decompensated Heart Failure

TerminatedNCT05346653

University of ChicagoAcute Decompensated Heart Failure

Start: 2023-05-22End: 2023-05-23Updated: 2024-09-04

Efficacy and Safety of Triple Therapy With Dulaglutide, SGLT2 Inhibitors, and Finerenone in Chinese Adults With Type 2 Diabetes and Chronic Kidney Disease

Not yet recruitingNCT07537088

First Affiliated Hospital of Wannan Medical CollegeCKD - Chronic Kidney Disease, T2DM (Type 2 Diabetes Mellitus)

Start: 2026-05-01End: 2027-07-01Target: 468Updated: 2026-04-22

Unknown Phase

Comparison of Type 2 Diabetes Pharmacotherapy Regimens

CompletedNCT05073692

Kaiser PermanenteCardiovascular Diseases, Type 2 Diabetes Mellitus

Start: 2021-07-01End: 2025-03-12Updated: 2025-11-21

Real-world Evaluation of GLP-1 Receptor Agonists (GLP-1RA) on Efficacy and Persistence, Adherence and Therapeutic Inertia Among Type 2 Diabetes Adults With Obesity

CompletedNCT05535322

Ana PalancaObesity, Type 2 Diabetes

Start: 2014-01-01End: 2022-09-01Updated: 2022-09-28

Speckle tracking echocardiographic study of gliflozins effect on rheumatic mitral regurgitation.

Active, not recruitingPACTR202511489850900

Assiut universityCardiology

Start: 2026-04-01Target: 216Updated: 2026-06-22

Related Papers

Rationale and design of Dapagliflozin vErsus SacubiTrIl-valsartaN therapY in Heart Failure with reduced ejection fraction (DESTINY-HF): a pragmatic randomised controlled trial protocol

BMJ Open2024-10-011 citations

Real-World Evaluation of GLP-1 Receptor Agonist Therapy Persistence, Adherence and Therapeutic Inertia Among Obese Adults with Type 2 Diabetes