Sevelamer

DRUG16 trials

Sponsors

National Center for Research Resources (NCRR), Nabi Biopharmaceuticals, Romanian Society of Nephrology, Karolinska Institutet, Shire

Conditions

ArteriosclerosisCalcinosisCalcium-Phosphorus Metabolism DisordersChronic Kidney DiseaseChronic Kidney Disease Stage 3-5Chronic Kidney Disease(CKD)Chronic Renal FailureDegenerative Heart Valve Disease

Phase 1

Comparing Absorption of Dietary Phosphorus When Administering FOSRENOL® or RENVELA® in Healthy Adult Volunteers

CompletedNCT00875017

ShireKidney Failure, Chronic

Start: 2009-04-20End: 2009-06-16Updated: 2021-06-15

DS2330b Alone and With Sevelamer in Patients on Chronic Hemodialysis

CompletedNCT03305471

Daiichi SankyoHyperphosphatemia

Start: 2017-08-17End: 2019-01-03Updated: 2019-03-25

Phase 2

Sevelamer in Proteinuric CKD

CompletedNCT01968759

Mario Negri Institute for Pharmacological ResearchChronic Kidney Disease

Start: 2013-10-31End: 2015-10-31Updated: 2015-10-12

Mechanism of Microbiome-induced Insulin Resistance in Humans (Aim 1)

CompletedNCT02124759

The University of Texas Health Science Center at San AntonioInsulin Sensitivity

Start: 2014-04-02End: 2020-03-30Updated: 2021-10-15

Mechanism of Microbiome-induced Insulin Resistance in Humans (Aim2)

CompletedNCT02127125

The University of Texas Health Science Center at San AntonioInsulin Sensitivity

Start: 2014-04-10End: 2018-09-10Updated: 2020-09-11

Phase 3

Nicotinamide Versus Sevelamer Hydrochloride on Phosphatemia Control on Chronic Hemodialysed Patients

TerminatedNCT01011699

Centre Hospitalier Universitaire, AmiensChronic Renal Failure, Hemodialysis

Start: 2010-01-31End: 2013-06-30Updated: 2016-05-16

Effect of Sevelamer on P-cresol Levels in CKD

Federico II UniversityChronic Kidney Disease Stage 3-5

Start: 2014-06-30Target: 200Updated: 2015-02-18

Phase 4

CARE-2 (Calcium Acetate [PhosLo®]/Sevelamer[Renagel®] Evaluation Study 2) for Heart Calcification in Dialysis Patients

CompletedNCT00211939

Nabi BiopharmaceuticalsArteriosclerosis, Calcinosis, Hyperparathyroidism, Secondary

Start: 2005-01-31End: 2007-03-31Updated: 2008-01-08

Sevelamer, FGF-23 and Endothelial Dysfunction in Chronic Kidney Disease (CKD)

CompletedNCT01135615

Gulhane School of MedicineWe Investigated the Relationship Between Plasma FGF23 Levels and Endothelial Dysfunction in a Sizable Series of Incident Stage 3-4 CKD Patients.

Start: 2008-01-31End: 2010-05-31Updated: 2011-07-22

Calcium-Phosphorus Regulation Therapy on Heart Valve Disease

RecruitingNCT06660524

China National Center for Cardiovascular DiseasesCalcium-Phosphorus Metabolism Disorders, Chronic Kidney Disease(CKD), Degenerative Heart Valve Disease +1

Start: 2024-03-01End: 2025-12-31Target: 196Updated: 2024-10-28

Unknown Phase

Parathyroid Hormone Levels in Relation to the Phosphorus Content of Meals

CompletedNCT00018135

National Center for Research Resources (NCRR)Renal Failure

Updated: 2005-06-24

Arterial Stiffness and Calcifications in Haemodialysis Patients on Sevelamer or Calcium Acetate

WithdrawnNCT00364000

Romanian Society of NephrologyHaemodialyzed Patients, Hyperphosphatemia

Start: 2012-01-31End: 2017-12-31Updated: 2017-12-22

Effect of Sevelamer on Glucose Tolerance and Insulin Sensitivity in Patients With Chronic Renal Failure (CKD)

WithdrawnNCT00837655

Karolinska InstitutetEnd-Stage Renal Disease, Hyperphosphatemia, Insulin Resistance +1

Start: 2009-01-31End: 2011-06-30Updated: 2012-09-26

Hypophosphatemic Rickets in Norway

Haukeland University HospitalHyperphosphatemia, Hypophosphatemia, Familial, Rickets

Start: 2009-12-31Target: 80Updated: 2016-08-31

Effect of Bile Acid Secretion and Sequestration on GLP-1 Secretion

CompletedNCT02445508

University Hospital, Gentofte, CopenhagenDiabetes Mellitus, Type 2

Start: 2015-05-31End: 2016-07-31Updated: 2017-05-03

GLP-1-mediated Gluco-metabolic Effects of Bile Acid Sequestration

CompletedNCT03739268

Steno Diabetes Center CopenhagenType 2 Diabetes Mellitus

Start: 2018-09-01End: 2021-09-01Updated: 2021-10-13

Related Papers

Effects of Sevelamer Carbonate in Patients With CKD and Proteinuria: The ANSWER Randomized Trial.

2019-04-2317 citations

Plasma p-cresol lowering effect of sevelamer in non-dialysis CKD patients: evidence from a randomized controlled trial.

2017-11-2018 citations