Sentinel® Cerebral Protection System

DEVICE3 trials

Sponsors

Boston Scientific Corporation, Malini Madhavan, China National Center for Cardiovascular Diseases

Conditions

Aortic Stenosis Treated With TAVIArrhythmiaAtrial FibrillationStrokeTranscatheter Aortic Valve Replacement (TAVR)

Unknown Phase

PROTECTED TAVR: Stroke PROTECTion With SEntinel During Transcatheter Aortic Valve Replacement

CompletedNCT04149535

Boston Scientific CorporationStroke

Start: 2020-02-07End: 2022-02-01Updated: 2023-02-02

Safety and Efficacy of the Sentinel Cerebral Protection Device in Atrial Fibrillation Ablation

RecruitingNCT04685317

Malini MadhavanArrhythmia, Atrial Fibrillation

Start: 2023-03-07End: 2027-06-01Target: 48Updated: 2026-07-21

A Clinical Study on the Use of the Sentinel Cerebral Protection Device During TAVR for the Prevention of Procedure-Related Stroke

Enrolling by invitationNCT07045233

China National Center for Cardiovascular DiseasesAortic Stenosis Treated With TAVI, Stroke, Transcatheter Aortic Valve Replacement (TAVR)

Start: 2025-06-01End: 2028-07-31Target: 200Updated: 2025-07-08

Related Papers

Cerebral Embolic Protection by Geographic Region

JAMA Cardiology2024-10-299 citations

Cerebral Embolic Protection during Transcatheter Aortic-Valve Replacement

New England Journal of Medicine2022-09-17259 citations

Efficacy and safety of cerebral embolic protection systems during transcatheter aortic valve replacement: a review of current clinical findings.

2021-07-216 citations