Reirradiation

RADIATION8 trials

Conditions

Abdominal CancerBreast Cancer RecurrentCarcinoma, Squamous Cell of Head and NeckFirst Progression of GlioblastomaHead and Neck NeoplasmNasopharyngeal CarcinomaNasopharyngeal DiseasesNasopharyngeal Neoplasms

Phase 1

aPBI Re-irradiation

Not yet recruitingNCT07612254

Dartmouth-Hitchcock Medical CenterBreast Cancer Recurrent

Start: 2026-06-03End: 2033-04-01Target: 30Updated: 2026-05-28

Phase 2

Reirradiation With Pembrolizumab in Locoregional Inoperable Recurrence or Second Primary Squamous Cell CA of the Head and Neck

CompletedNCT02289209

Dan ZandbergCarcinoma, Squamous Cell of Head and Neck, Recurrent Head and Neck Cancer

Start: 2016-03-09End: 2024-08-31Updated: 2025-03-06

IMRT Combined With Toripalimab in Unresectable Locally Recurrent Nasopharyngeal Carcinoma.

NCT03854838

Sun Yat-sen UniversityHead and Neck Neoplasm, Nasopharyngeal Carcinoma, Nasopharyngeal Diseases +1

Start: 2019-05-01End: 2023-02-01Updated: 2022-04-29

Phase 3

Lomustine With and Without Reirradiation for First Progression of Glioblastoma: a Randomized Phase III Study

RecruitingNCT05904119

European Organisation for Research and Treatment of Cancer - EORTCFirst Progression of Glioblastoma

Start: 2024-03-15End: 2028-02-01Target: 411Updated: 2026-06-08

Unknown Phase

Radiotherapy & Total Neoadjuvant Therapy for Recurrent Rectal Cancer in Previously Irradiated Patients, an Italian Association for Radiotherapy and Clinical Oncology (AIRO)-GI Platform: a Multi-centre Prospective Observational Study

RecruitingNCT05984576

Fondazione Policlinico Universitario Agostino Gemelli IRCCSRectal Neoplasm

Start: 2023-06-21End: 2031-06-05Target: 88Updated: 2023-08-09

Ablative Stereotactic MR-Guided Adaptive Reirradiation

Active, not recruitingNCT06397573

Baptist Health South FloridaAbdominal Cancer, Pelvic Cancer

Start: 2024-06-05End: 2027-06-01Target: 10Updated: 2026-02-17

Prospective RegIstry for Oncologic Reirradiation (PRIOR-DK)

Not yet recruitingNCT07528339

University of AarhusRadiotherapy Side Effect

Start: 2026-04-01End: 2037-03-31Target: 500Updated: 2026-04-14

Reirradiation and Total Ablative Strategies for Recurrent Gynecologic Cancer

RecruitingNCT07667192

Affidea Nu-med Center of Oncological DIagnostics and TherapyPrimary Peritoneal Cancer, Recurrent Cervical Cancer, Recurrent Fallopian Tube Cancer +5

Start: 2026-06-11End: 2036-12-01Target: 500Updated: 2026-06-24

2024-12-18

Lomustine with or without reirradiation for first progression of glioblastoma, LEGATO, EORTC-2227-BTG: study protocol for a randomized phase III study

Trials2024-06-0714 citations

A phase II trial of reirradiation combined with pembrolizumab in patients with locoregional inoperable recurrence or second primary squamous cell carcinoma of the head and neck (HNSCC).

Journal of Clinical Oncology2024-06-01

Efficacy of sequential chemoradiotherapy combined with toripalimab in de novo metastatic nasopharyngeal carcinoma: A phase II trial.

2023-11-1014 citations

Toripalimab plus intensity-modulated radiotherapy for recurrent nasopharyngeal carcinoma: an open-label single-arm, phase II trial

Journal for ImmunoTherapy of Cancer2021-11-0140 citations

Toripalimab plus intensity-modulated radiotherapy for recurrent nasopharyngeal carcinoma: An open-label single-arm, phase II trial.

Journal of Clinical Oncology2021-05-203 citations