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Pycnogenol

DIETARY_SUPPLEMENT7 trials

Sponsors

National Center for Complementary and Integrative Health (NCCIH), University of Wisconsin, Madison, University of Zurich, University of Arizona, Nina Hermans

Conditions

ADHDBreastCancerCardiac FibrosisCoronary Artery DiseaseDiastolic DysfunctionGulf War IllnessLymphedema

Phase 2

Pycnogenol for the Treatment of Lymphedema of the Arm in Breast Cancer Survivors
CompletedNCT00064857
National Center for Complementary and Integrative Health (NCCIH)Breast, Cancer, Lymphedema
Start: 2003-08-31End: 2007-08-31Target: 26Updated: 2008-04-22
Pycnogenol for the Treatment of Lymphedema
CompletedNCT00214032
University of Wisconsin, MadisonLymphedema
Start: 2002-05-31End: 2007-01-31Updated: 2015-10-05
Effects of Pycnogenol on Cardiac Fibrosis and Diastolic Dysfunction in Aged Hypertensive Subjects
TerminatedNCT00952627
University of ArizonaCardiac Fibrosis, Diastolic Dysfunction
Start: 2009-07-31End: 2011-07-31Updated: 2013-12-17

Phase 3

Effect of Pycnogenol® on ADHD
CompletedNCT02700685
Nina HermansADHD
Start: 2017-09-01End: 2020-11-20Updated: 2021-04-28

Unknown Phase

Pycnogenol and Endothelial Function in Coronary Artery Disease
CompletedNCT00641758
University of ZurichCoronary Artery Disease
Start: 2008-03-31End: 2009-12-31Target: 25Updated: 2010-02-10
Effects of Botanical Microglia Modulators in Gulf War Illness
CompletedNCT02909686
University of Alabama at BirminghamGulf War Illness
Start: 2016-07-31End: 2022-09-30Updated: 2025-01-24
Impact of Pycnogenol® on Gingival Inflammation
CompletedNCT05786820
Wuerzburg University HospitalPeriodontitis
Start: 2022-03-17End: 2024-07-20Updated: 2024-08-09

Related Papers

Impact of a Dietary Supplementation with French Maritime Pine Bark Extract Pycnogenol® on Salivary and Serum Inflammatory Biomarkers During Non-Surgical Periodontal Therapy—A Randomized Placebo-Controlled Double-Blind Trial
Nutrients2025-04-302 citations
A Placebo-Controlled, Pseudo-Randomized, Crossover Trial of Botanical Agents for Gulf War Illness: Reishi Mushroom (Ganoderma lucidum), Stinging Nettle (Urtica dioica), and Epimedium (Epimedium sagittatum)
International Journal of Environmental Research and Public Health2021-04-012 citations
A Placebo-Controlled, Pseudo-Randomized, Crossover Trial of Botanical Agents for Gulf War Illness: Resveratrol (Polygonum cuspidatum), Luteolin, and Fisetin (Rhus succedanea)
International Journal of Environmental Research and Public Health2021-03-0326 citations
A Placebo-Controlled, Pseudo-Randomized, Crossover Trial of Botanical Agents for Gulf War Illness: Curcumin (Curcuma longa), Boswellia (Boswellia serrata), and French Maritime Pine Bark (Pinus pinaster)
International Journal of Environmental Research and Public Health2021-03-0318 citations
Effect of Pycnogenol® on attention-deficit hyperactivity disorder (ADHD): study protocol for a randomised controlled trial.
2017-03-2820 citations