PSILOCYBINE

DRUG7 trials

Conditions

Alcohol use disorderBasic ScienceHealthyHematopoietic and Lymphatic System NeoplasmMalignant Solid Neoplasmalcohol use disorderdepressiondepressive symptoms

Phase 1

The Neurobiological Effect of 5-HT2AR Modulation

RecruitingNCT03289949

Gitte Moos KnudsenBasic Science

Start: 2017-03-03End: 2030-06-01Target: 200Updated: 2024-12-16

Phase 2

Psilocybin in alcohol use disorder with comorbid depression - Randomized double-blind controlled pilot study.

CompletedCTIS2023-506647-42-00

Centre Hospitalier Universitaire De Nimes, Centre Hospitalier Universitaire De Nimesalcohol use disorder

Start: 2024-02-05End: 2025-03-05Target: 30Updated: 2024-03-21

Evaluation of the effect of a single dose of psilocybin on neural correlates of cognitive control in patients with CNEP (psychogenic nonepileptic seizures): a single-arm, open-label pilot study.

Active, not recruitingCTIS2023-509679-17-00

Centre Hospitalier Universitaire De Nimespsychogenic non-epileptic seizures

Start: 2024-11-05Target: 10Updated: 2025-01-13

Effect of psilocybin on the positive valence system in treatment-resistant depression: a pilot clinical neuroimaging study

CompletedCTIS2022-501092-11-00

Centre Hospitalier Universitaire De Nimesdepression, mental disorders

Start: 2024-11-05End: 2025-09-26Target: 20Updated: 2024-09-26

Psilocybin With Psychotherapy for Improving Chronic Pain in Cancer Patients Requiring Opioids

Not yet recruitingNCT06827054

Roswell Park Cancer InstituteHematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm

Start: 2026-08-15End: 2027-05-05Target: 20Updated: 2026-06-22

Phase 3

ERPPAD - Efficacy in Relapse Prevention: Psilocybin in Alcohol use disorder with Depressive symptoms

Not yet recruitingCTIS2025-525069-65-00

Centre Hospitalier Universitaire De NimesAlcohol use disorder, depressive symptoms

Target: 172Updated: 2026-06-05

Unknown Phase

Beyond the Self and Back: Neuropharmacological Mechanisms Underlying the Dissolution of the Self

CompletedNCT03736980

University of ZurichHealthy

Start: 2013-10-01End: 2018-12-31Updated: 2020-11-04

Related Papers

Psilocybin’s effect on human brain synaptic plasticity

Translational Psychiatry2026-07-15

Effects of psilocybin on sleep quality and brain microstructure in chronic cluster headache

Journal of Psychopharmacology2026-05-29

Ketamine induces multiple individually distinct whole-brain functional connectivity signatures

eLife2024-03-1121 citations

Psilocybin-Induced Mystical-Type Experiences are Related to Persisting Positive Effects: A Quantitative and Qualitative Report

Frontiers in Pharmacology2022-03-0981 citations