Proxalutamide

DRUG7 trials

Conditions

Androgenetic AlopeciaBenign Prostatic HyperplasiaCOVID-19Covid19Metastatic Breast CancerNeoadjuvant Therapy \High Risk Prostate CancerProstate CancerSARS (Severe Acute Respiratory Syndrome)

Phase 1

Safety, Tolerability, and Pharmacokinetics of Proxalutamide Therapy in Women With Metastatic Breast Cancer

CompletedNCT04103853

Suzhou Kintor Pharmaceutical Inc,Metastatic Breast Cancer

Start: 2017-09-06End: 2020-06-30Updated: 2021-09-24

Phase 2

Neoadjuvant Therapy With Proxalutamide Combined With Androgen Deprivation Therapy（ADT）for High Risk Prostate Cancer

NCT05076851

Hongqian GuoNeoadjuvant Therapy \High Risk Prostate Cancer

Start: 2021-06-17End: 2022-10-31Target: 2Updated: 2021-10-13

Phase 3

Proxalutamide Treatment for Hospitalized COVID-19 Patients

CompletedNCT04728802

Applied Biology, Inc.Covid19, SARS (Severe Acute Respiratory Syndrome)

Start: 2021-02-01End: 2021-04-15Updated: 2021-06-24

Proxalutamide Treatment for COVID-19 Female Outpatients

WithdrawnNCT04853134

Applied Biology, Inc.Covid19, SARS-CoV Infection

Start: 2020-11-01End: 2021-12-01Updated: 2022-03-04

Proxalutamide Treatment for COVID-19 Patients in Intensive Care Unit

WithdrawnNCT04853927

Applied Biology, Inc.Covid19, SARS (Severe Acute Respiratory Syndrome)

Start: 2021-02-08End: 2021-12-31Updated: 2022-03-04

The South Proxa-Rescue AndroCoV Trial Against COVID-19

CompletedNCT05126628

Corpometria InstituteCOVID-19

Start: 2021-03-06End: 2021-04-15Updated: 2021-11-19

Unknown Phase

Anti-Androgen Treatment for COVID-19

CompletedNCT04446429

Applied Biology, Inc.Androgenetic Alopecia, Benign Prostatic Hyperplasia, COVID-19 +3

Start: 2020-10-21End: 2021-01-21Updated: 2021-12-10

2022-09-284 citations

RETRACTED: Proxalutamide Reduces the Rate of Hospitalization for COVID-19 Male Outpatients: A Randomized Double-Blinded Placebo-Controlled Trial

Frontiers in Medicine2021-07-1946 citations

Abstract 711: Repurposing 2nd generation androgen receptor antagonist Proxalutamide to treat COVID-19

Cancer Research2021-07-01

A phase Ib study of proxalutamide (GT0918) in women with androgen receptor-positive metastatic breast cancer.

Journal of Clinical Oncology2021-05-201 citations

5‐alpha‐reductase inhibitors are associated with reduced frequency of COVID‐19 symptoms in males with androgenetic alopecia

Journal of the European Academy of Dermatology and Venereology2020-11-0248 citations