Privigen 100 mg/ml solution for infusion
Sponsors
Sorlandet Sykehus HF, Janssen - Cilag International, Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC), Pfizer Inc., Janssen Cilag International
Conditions
-Peripheral neuropathy clinically defined:
*Pure sensitive (lymph node disease) or sensorimotor neuropathies
*Proved EMG-Primary Sjögren's syndrome defined as per the European and American
criteriaCOVID-19 and Severely Impaired B-cell FunctionChronic Inflammatory Demyelinating PolyneuropathyChronic inflammatory demyelinating polyneuropathy (CIDP)Idiopathic painful small fiber neuropathy or sensory neuronopathy.Kawasaki diseaseKidney Transplantation
BKV infection
Phase 1
Phase 2
Effect of intravenous immunoglobulins on painful sensory neuropathy evaluated by aggregated N-of-one trials
Not yet recruitingCTIS2022-501717-31-00
Target: 30Updated: 2024-12-19
A PHASE-2B, DOUBLE-BLIND, RANDOMIZED CONTROLLED TRIAL TO EVALUATE THE ACTIVITY AND SAFETY OF INEBILIZUMAB IN ANTI-NMDA RECEPTOR ENCEPHALITIS AND ASSESS MARKERS OF DISEASE (EXTINGUISH)
RecruitingCTIS2023-504686-23-00
Start: 2024-12-10Target: 26Updated: 2025-11-13
Phase 2/3, Multistage, Multicenter, Randomized, Double-Blind, Placebo-Controlled Parallel Group Withdrawal Study to Evaluate the Efficacy and Safety of Nipocalimab Administered to Adults with Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
RecruitingCTIS2023-508425-28-00
Start: 2022-10-24Target: 42Updated: 2026-01-07
A Phase 3 Randomized Study Comparing Teclistamab in Combination with Daratumumab SC (Tec-Dara) versus Daratumumab SC, Pomalidomide, and Dexamethasone (DPd) or Daratumumab SC, Bortezomib, and Dexamethasone (DVd) in Participants with Relapsed or Refractory Multiple Myeloma
Active, not recruitingCTIS2023-503441-55-00
Start: 2021-10-14Target: 310Updated: 2025-09-27
Randomized Open Label Trial Evaluating Efficacy and Safety of Intravenous Immunoglobulin (IVIg, Privigen) as Add-on to SoC Versus SoC Alone for Coronavirus Disease 2019 (COVID-19) in Patients with Severely Impaired B-cell Function
Not yet recruitingCTIS2025-522756-97-00
Target: 92Updated: 2026-02-06
Phase 3
A Phase 3 Randomized Study Comparing Talquetamab in Combination with Pomalidomide (Tal-P), Talquetamab in Combination with Teclistamab (Tal-Tec), and Investigator’s Choice of Either Elotuzumab, Pomalidomide, and Dexamethasone (EPd) or Pomalidomide, Bortezomib, and Dexamethasone (PVd) in Participants with Relapsed or Refractory Myeloma who Have Received 1 to 4 Prior Lines of Therapy Including an Anti-CD38 Antibody and Lenalidomide
Active, not recruitingCTIS2022-502446-27-00
Start: 2024-02-26Target: 453Updated: 2026-01-13
C1071007 - MAGNETISMM-7
A RANDOMIZED, 2-ARM, PHASE 3 STUDY OF ELRANATAMAB (PF-06863135) VERSUS LENALIDOMIDE IN PATIENTS WITH NEWLY DIAGNOSED MULTIPLE MYELOMA AFTER UNDERGOING AUTOLOGOUS STEM-CELL TRANSPLANTATION
Active, not recruitingCTIS2023-508897-27-00
Start: 2022-04-28Target: 377Updated: 2025-11-27
C1071032 - MAGNETISMM-32 A PHASE 3, OPEN-LABEL STUDY OF ELRANATAMAB MONOTHERAPY VERSUS ELOTUZUMAB, POMALIDOMIDE, DEXAMETHASONE (EPd) OR POMALIDOMIDE, BORTEZOMIB, DEXAMETHASONE (PVd) OR CARFILZOMIB, DEXAMETHASONE (Kd) IN PARTICIPANTS WITH RELAPSED REFRACTORY MULTIPLE MYELOMA WHO RECEIVED PRIOR ANTI-CD38 DIRECTED THERAPY
RecruitingCTIS2023-507871-23-00
Start: 2024-05-27Target: 394Updated: 2026-01-27
A Phase 3 Randomized Study Comparing Talquetamab SC in Combination With Daratumumab SC and Pomalidomide (Tal-DP) or Talquetamab SC in Combination With Daratumumab SC (Tal-D) Versus Daratumumab SC, Pomalidomide and Dexamethasone (DPd), in Participants With Relapsed or Refractory Multiple Myeloma who Have Received at Least 1 Prior Line of Therapy
Active, not recruitingCTIS2023-503467-41-00
Start: 2022-10-12Target: 310Updated: 2026-01-27
A Phase 3 Randomized Study Comparing Teclistamab Monotherapy versus Pomalidomide, Bortezomib, Dexamethasone (PVd) or Carfilzomib, Dexamethasone (Kd) in Participants with Relapsed or Refractory Multiple Myeloma who have Received 1 to 3 Prior Lines of Therapy, Including an Anti-CD38 Monoclonal Antibody and Lenalidomide
Active, not recruitingCTIS2023-503444-13-00
Start: 2023-03-29Target: 291Updated: 2025-10-23
Intravenous Immunoglobulins for Prevention of BKV Viremia in Kidney Transplant
Recipients According to BKV genotype-specific Neutralizing Antibody Titers at the
day of transplantation: A Multicenter Study -BKANIG
RecruitingCTIS2024-515243-37-00
Start: 2022-08-21Target: 664Updated: 2024-07-12
Influencing Progression of Airway Disease in Primary Antibody Deficiency
Not yet recruitingCTIS2024-513124-41-00
Target: 100Updated: 2024-07-12
C1071006 – An Open-Label, 2-Arm, Multicenter, Randomized Phase 3 Study To Evaluate The Efficacy And Safety of Elranatamab (PF-06863135) + Daratumumab + Lenalidomide Versus Daratumumab + Lenalidomide + Dexamethasone in Transplant-Ineligible or Transplant-Deferred Participants With Newly Diagnosed Multiple Myeloma
RecruitingCTIS2024-514139-50-00
Start: 2022-11-14Target: 558Updated: 2025-12-04
A Phase 3 Randomized Study Comparing Teclistamab in Combination with Daratumumab SC and Lenalidomide (Tec-DR) and Talquetamab in Combination with Daratumumab SC and Lenalidomide (Tal-DR) versus Daratumumab SC, Lenalidomide, and Dexamethasone (DRd) in Participants with Newly Diagnosed Multiple Myeloma Who are Either Ineligible or not Intended for Autologous Stem Cell Transplant as Initial Therapy
RecruitingCTIS2023-503442-30-00
Start: 2022-10-14Target: 563Updated: 2025-09-02
C1071005 - MAGNETISMM-5: AN OPEN-LABEL, 3-ARM, MULTICENTER, RANDOMIZED PHASE 3 STUDY TO EVALUATE THE EFFICACY AND SAFETY OF ELRANATAMAB (PF-06863135) MONOTHERAPY AND ELRANATAMAB + DARATUMUMAB VERSUS DARATUMUMAB + POMALIDOMIDE + DEXAMETHASONE IN PARTICIPANTS WITH RELAPSED/REFRACTORY MULTIPLE MYELOMA WHO HAVE RECEIVED AT LEAST 1 PRIOR LINE OF THERAPY INCLUDING LENALIDOMIDE AND A PROTEASOME INHIBITOR
Active, not recruitingCTIS2023-509208-14-00
Start: 2021-09-28Target: 414Updated: 2025-10-01
Prospective, randomised, placebo-controlled study of polyvalent intravenous immunoglobulins for the treatment of primary Sjögren's syndrome associated painful sensory neuropathies
CompletedCTIS2024-517309-95-00
Start: 2019-06-19End: 2025-04-10Target: 24Updated: 2024-10-08
Randomized, parallel study of subcutaneous versus intravenous immunoglobulin in treatment-naïve patients with chronic inflammatory demyelinating polyneuropathy
Not yet recruitingCTIS2024-515898-96-01
Target: 60Updated: 2024-10-15
ANACOMP. A RANDOMIZED PHASE III MULTICENTER TRIAL COMPARING THE EFFICACY AND SAFETY OF ANAKINRA VERSUS INTRAVENOUS IMMUNOGLOBULIN (IVIG) RETREATMENT, IN PATIENTS WITH KAWASAKI DISEASE WHO FAILED TO RESPOND TO INITIAL STANDARD IVIG TREATMENT
SuspendedCTIS2024-516244-25-00
Start: 2024-11-06Target: 84Updated: 2025-12-30
A phase 3, open-label, controlled, randomized study of newly diagnosed multiple myeloma treatment, designed to evaluate the efficacy and safety of the elranatamab-lenalidomide combination as a replacement for chemotherapy followed by autologous stem cell transplant in the consolidation phase, and to compare elranatamab with standard of care in the maintenance phase (ElLen; IFM 2025-01)
RecruitingCTIS2024-516418-39-00
Start: 2025-07-09Target: 824Updated: 2025-12-15