Post-operative radiation therapy

RADIATION3 trials

Sponsors

Radiation Therapy Oncology Group, Memorial Sloan Kettering Cancer Center, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Conditions

HNSCCHead CancerHead Cancer NeckHead and Neck CancerHead and Neck Squamous Cell CarcinomaNeck CancerRadiation ToxicityXerostomia

Phase 1

A Study of Cemiplimab With Chemotherapy and Immunotherapy in People With Head and Neck Cancer

RecruitingNCT04722523

Memorial Sloan Kettering Cancer CenterHead and Neck Cancer, Head and Neck Squamous Cell Carcinoma, Head Cancer +3

Start: 2021-01-20End: 2027-06-20Target: 40Updated: 2026-07-21

Phase 2

Salivary Gland Surgery Before Radiation Therapy in Preventing Radiation-Caused Xerostomia in Patients With Head and Neck Cancer

CompletedNCT00068237

Radiation Therapy Oncology GroupHead and Neck Cancer, Radiation Toxicity, Xerostomia

Start: 2003-08-31End: 2016-12-31Updated: 2019-02-05

Tirelizumab in Combination With Carboplatin and Polymeric Micellar Paclitaxel for Neoadjuvant Therapy in cN+ HNSCC

Not yet recruitingNCT06366945

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityHead and Neck Cancer, Head and Neck Squamous Cell Carcinoma, Head Cancer Neck +1

Start: 2024-04-20End: 2029-05-30Target: 85Updated: 2024-04-16

Related Papers

Neoadjuvant cemiplimab with platinum-doublet chemotherapy and cetuximab in locoregionally advanced head & neck squamous cell carcinoma (HNSCC): Updated pathologic response and survival.

Journal of Clinical Oncology2025-05-28

Neoadjuvant cemiplimab with platinum-doublet chemotherapy and cetuximab to de-escalate surgery and omit adjuvant radiation in locoregionally advanced head & neck squamous cell carcinoma (HNSCC).

Journal of Clinical Oncology2023-06-017 citations

A pilot study of neoadjuvant cemiplimab with platinum-doublet chemotherapy and cetuximab in patients with resectable, locally advanced head and neck squamous cell carcinoma (HNSCC).

Journal of Clinical Oncology2022-06-011 citations