PIPAC

PROCEDURE14 trials

Conditions

Adenocarcinoma PancreasAdvanced Epithelial Ovarian CancerAppendix CancerAscitesCUPChemotherapeutic ToxicityChemotherapy EffectColo-rectal Cancer

Phase 1

PIPAC for Peritoneal Metastases

SuspendedNCT04956068

National Cancer Centre, SingaporePeritoneal Metastases

Start: 2021-05-20End: 2026-11-01Target: 25Updated: 2026-05-13

Pressurized Intraperitoneal Aerosolized Chemotherapy (PIPAC) in Patients With Peritoneal Metastasis From Pancreatic Adenocarcinoma

RecruitingNCT07253662

Northwell HealthAdenocarcinoma Pancreas

Start: 2026-01-11End: 2027-12-30Target: 10Updated: 2026-06-03

Phase 2

Treating Peritoneal Carcinomatosis With PIPAC

CompletedNCT02320448

Michael Bau MortensenPeritoneal Carcinomatosis

Start: 2015-03-31End: 2017-08-31Updated: 2017-09-12

Adjuvant Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) in Resected High Risk Colon Cancer Patients

RecruitingNCT03280511

Michael Bau MortensenColo-rectal Cancer, Peritoneal Carcinomatosis, Peritoneal Metastases +1

Start: 2017-12-14End: 2027-03-01Target: 60Updated: 2022-10-06

Treatment of Peritoneal Carcinomatosis With Pressurized IntraPeritoneal Aerosol Chemotherapy -

CompletedNCT03287375

Michael Bau MortensenChemotherapeutic Toxicity, Chemotherapy Effect, Histologic Progression +4

Start: 2016-12-01End: 2022-10-01Updated: 2022-10-07

Treatment of Malignant Peritoneal Mesothelioma (MESOTIP)

SuspendedNCT03875144

Institut du Cancer de Montpellier - Val d'AurellePeritoneal Carcinomatosis, Peritoneal Mesothelioma

Start: 2020-09-10End: 2027-06-01Target: 66Updated: 2026-02-09

Second Line Oxaliplatin Based Chemotherapy Alone Versus Oxaliplatin Based PIPAC and Chemotherapy in Colorectal Peritoneal Carcinomatosis : A Phase II Randomize Mutli-centric Study

NCT04734691

Sleiman Marwan-JulienPeritoneal Carcinomatosis

Start: 2021-10-31End: 2024-11-30Target: 50Updated: 2021-02-02

Systemic Antitumor Treatment with or Without Pressurized Intraperitoneal Aerosol Chemotherapy for Colon Peritoneal Metastases (PIPOX02)

Not yet recruitingNCT06681038

Institut Cancerologie de l'OuestPeritoneal Metastases from Colorectal Cancer

Start: 2025-02-28End: 2029-08-31Target: 114Updated: 2024-11-08

Intensification Treatment of Ovarian Cancer by PIPAC

RecruitingNCT07514494

Moscow Regional Oncological DispensaryAdvanced Epithelial Ovarian Cancer, Peritoneal Carcinomatosis

Start: 2025-04-02End: 2030-04-02Target: 160Updated: 2026-04-07

Phase 3

A Randomized Controlled Trial Evaluating the Feasibility and Preliminary Efficacy of Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) in Advanced Epithelial Ovarian Cancer

RecruitingNCT07544030

tongweihuaOvarian Cancer

Start: 2025-11-10End: 2027-11-10Target: 60Updated: 2026-05-11

Unknown Phase

Register Study of Patients With Peritoneal Carcinomatosis Treated With PIPAC (Pressurized Intra-peritoneal Aerosol-Chemotherapy)

NCT03100708

University of LeipzigPeritoneal Carcinomatosis

Start: 2016-04-30End: 2021-04-30Target: 500Updated: 2019-09-25

International Registry of Patients Treated With Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC)

NCT03210298

Sabine RhodeAppendix Cancer, Ascites, Chemotherapeutic Toxicity +12

Start: 2016-01-31End: 2022-09-30Target: 1000Updated: 2019-10-08

Oncological Benefits of Pressured Intraperitoneal Aerosol Chemotherapy (PIPAC) in Patients With T3-4 Gastric Cancer Cyt-

RecruitingNCT04595929

St. Petersburg State Pavlov Medical UniversityGastric Cancer, Peritoneal Carcinomatosis

Start: 2020-02-10End: 2029-01-10Target: 304Updated: 2020-11-25

Cost and Effectiveness of Pressurized Intraperitoneal Aerosol Chemotherapy in Patients With Peritoneal Carcinoma.

CompletedNCT04779385

University Hospital, GrenobleEvaluate the Cost of a PIPAC Procedure and the Associated Hospital Stay in France

Start: 2020-11-16End: 2021-03-30Updated: 2021-05-05

Cancer Research2026-04-17

D2 Gastrectomy in Combination with Simultaneous Pressurized Intraperitoneal Chemotherapy (PIPAC) for Gastric Cancer: Immediate Results of the GASPACCO Clinical Trial Protocol. Safety Analysis

Voprosy Onkologii2024-11-30

Peritoneal regression grading score (PRGS): first evidence for independent predictive and prognostic significance

Pleura and Peritoneum2023-05-1813 citations

Application of the method of intraoperative intraperitoneal aerosol chemotherapy (PIPAC) in complex treatment of locally advanced gastric cancer with cytologically negative peritoneal lavages: the protocol for GASPACCO clinical trial

Voprosy Onkologii2022-12-27

Pressurized intraperitoneal aerosol chemotherapy (PIPAC) in patients with peritoneal surface malignancies (PSM): a prospective single-center registry study

Journal of Cancer Research and Clinical Oncology2022-12-1310 citations

Patient-reported outcomes during repetitive oxaliplatin-based pressurized intraperitoneal aerosol chemotherapy for isolated unresectable colorectal peritoneal metastases in a multicenter, single-arm, phase 2 trial (CRC-PIPAC).

2021-11-1010 citations

Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) in patients with peritoneal metastasized colorectal, appendiceal and small bowel cancer

Tumori Journal2019-08-3034 citations

Detection of free intraperitoneal tumour cells in peritoneal lavage fluid from patients with peritoneal metastasis before and after treatment with pressurised intraperitoneal aerosol chemotherapy (PIPAC)

Journal of Clinical Pathology2019-02-1219 citations

Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) for Peritoneal Metastases in Solid Organ Graft Recipients: First Experience

Annals of Transplantation2019-01-156 citations

Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) as an outpatient procedure

Pleura and Peritoneum2018-11-2535 citations

Feasibility, Safety, and Efficacy of Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) for Peritoneal Metastasis: A Registry Study

Gastroenterology Research and Practice2018-10-2468 citations

Evaluation der druckinduzierten intraperitonealen Aerosol-Chemotherapie (PIPAC) bei Patienten mit fortgeschrittener Peritonealkarzinose

Zeitschrift für Gastroenterologie2018-08-01

Treatment of peritoneal carcinomatosis with Pressurized IntraPeritoneal Aerosol Chemotherapy – PIPAC-OPC2

Pleura and Peritoneum2018-06-0132 citations

Adjuvant Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) in resected high-risk colon cancer patients – study protocol for the PIPAC-OPC3 Trial. A prospective, controlled phase 2 Study

Pleura and Peritoneum2018-06-0125 citations

Prospective, single-center implementation and response evaluation of pressurized intraperitoneal aerosol chemotherapy (PIPAC) for peritoneal metastasis

Therapeutic Advances in Medical Oncology2018-01-0178 citations

Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) in Gastric Cancer Patients with Peritoneal Metastasis (PM): Results of a Single-Center Experience and Register Study

Journal of the Korean Gastric Cancer Association2018-01-0174 citations