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Photon therapy

RADIATION6 trials

Sponsors

M.D. Anderson Cancer Center, St. Jude Children's Research Hospital, Technische Universität Dresden, University of Aarhus, Erasmus Medical Center

Conditions

EpendymomaGliomaNon-Small Cell Lung CancerNon-Small-Cell Lung CarcinomaProstate CancerRadiotherapy Side EffectRadiotherapy; Complications

Phase 2

Trial of Image-Guided Adaptive Conformal Photon vs Proton Therapy, With Concurrent Chemotherapy, for Locally Advanced Non-Small Cell Lung Carcinoma: Treatment Related Pneumonitis and Locoregional Recurrence
CompletedNCT00915005
M.D. Anderson Cancer CenterNon-Small-Cell Lung Carcinoma
Start: 2009-06-30End: 2020-02-24Updated: 2020-05-26
A Trial of Surgery and Fractionated Re-Irradiation for Recurrent Ependymoma
Active, not recruitingNCT02125786
St. Jude Children's Research HospitalEpendymoma
Start: 2014-05-07End: 2028-05-01Updated: 2026-02-24

Unknown Phase

Proton Therapy to Reduce Acute Normal Tissue Toxicity in Locally Advanced Non-small-cell Lung Cancer
NCT02731001
Technische Universität DresdenNon-Small Cell Lung Cancer
Start: 2016-08-31End: 2025-12-31Target: 98Updated: 2021-08-19
Protons vs. Photons for High-risk Prostate Cancer
Active, not recruitingNCT05350475
University of AarhusProstate Cancer, Radiotherapy Side Effect
Start: 2022-03-01End: 2038-12-01Target: 102Updated: 2026-08-13
Short Term Outcomes After PRoton and PhotoN RadiOtherapy for IDH Mutated Grade 2 and 3 Gliomas
RecruitingNCT06180434
Erasmus Medical CenterGlioma, Radiotherapy; Complications
Start: 2024-05-01End: 2025-11-01Target: 320Updated: 2024-10-15
Proton vs. Photon Radiotherapy for Patients With WHO Grade 2-3 Glioma
RecruitingNCT07750457
University Hospital, EssenGlioma
Start: 2019-01-15End: 2033-12-31Target: 80Updated: 2026-08-24

Related Papers

Prediction of Grade 4 radiation-induced lymphopenia during chemoradiation therapy for lung cancer patients: Insights from two past trials.
2025-04-01
Proton therapy planning and image-guidance strategies within a randomized controlled trial for high-risk prostate cancer
Clinical and Translational Radiation Oncology2023-04-256 citations
Coronary artery calcium score on standard of care oncologic CT scans for the prediction of adverse cardiovascular events in patients with non-small cell lung cancer treated with concurrent chemoradiotherapy
Frontiers in Cardiovascular Medicine2022-12-0218 citations
Toxicity and Survival After Intensity-Modulated Proton Therapy Versus Passive Scattering Proton Therapy for NSCLC.
2020-10-2234 citations
Perspectives on the model-based approach to proton therapy trials: A retrospective study of a lung cancer randomized trial.
2020-03-275 citations
Association of lung fluorodeoxyglucose uptake with radiation pneumonitis after concurrent chemoradiation for non-small cell lung cancer.
2017-05-119 citations
PRONTOX - proton therapy to reduce acute normal tissue toxicity in locally advanced non-small-cell lung carcinomas (NSCLC): study protocol for a randomised controlled trial.
2016-11-1515 citations
Bayesian randomized trial comparing intensity modulated radiation therapy versus passively scattered proton therapy for locally advanced non-small cell lung cancer.
Journal of Clinical Oncology2016-05-2034 citations
Normal-lung uptake of fluorodeoxyglucose, patient-reported symptoms, and clinician-rated radiation pneumonitis in patients with non-small cell lung cancer treated with chemoradiation.
Journal of Clinical Oncology2016-05-201 citations