Photon therapy

RADIATION5 trials

Sponsors

M.D. Anderson Cancer Center, St. Jude Children's Research Hospital, Technische Universität Dresden, University of Aarhus, Erasmus Medical Center

Conditions

EpendymomaGliomaNon-Small Cell Lung CancerNon-Small-Cell Lung CarcinomaProstate CancerRadiotherapy Side EffectRadiotherapy; Complications

Phase 2

Trial of Image-Guided Adaptive Conformal Photon vs Proton Therapy, With Concurrent Chemotherapy, for Locally Advanced Non-Small Cell Lung Carcinoma: Treatment Related Pneumonitis and Locoregional Recurrence

CompletedNCT00915005

M.D. Anderson Cancer CenterNon-Small-Cell Lung Carcinoma

Start: 2009-06-30End: 2020-02-24Updated: 2020-05-26

A Trial of Surgery and Fractionated Re-Irradiation for Recurrent Ependymoma

Active, not recruitingNCT02125786

St. Jude Children's Research HospitalEpendymoma

Start: 2014-05-07End: 2028-05-01Updated: 2026-02-24

Unknown Phase

Proton Therapy to Reduce Acute Normal Tissue Toxicity in Locally Advanced Non-small-cell Lung Cancer

Technische Universität DresdenNon-Small Cell Lung Cancer

Start: 2016-08-31End: 2025-12-31Target: 98Updated: 2021-08-19

Protons Vs. Photons for High-risk Prostate Cancer

RecruitingNCT05350475

University of AarhusProstate Cancer, Radiotherapy Side Effect

Start: 2022-03-01End: 2037-03-01Target: 400Updated: 2025-03-07

Short Term Outcomes After PRoton and PhotoN RadiOtherapy for IDH Mutated Grade 2 and 3 Gliomas

RecruitingNCT06180434

Erasmus Medical CenterGlioma, Radiotherapy; Complications

Start: 2024-05-01End: 2025-11-01Target: 320Updated: 2024-10-15

Related Papers

Prediction of Grade 4 radiation-induced lymphopenia during chemoradiation therapy for lung cancer patients: Insights from two past trials.

2025-04-01

Proton therapy planning and image-guidance strategies within a randomized controlled trial for high-risk prostate cancer

Clinical and Translational Radiation Oncology2023-04-256 citations

Coronary artery calcium score on standard of care oncologic CT scans for the prediction of adverse cardiovascular events in patients with non-small cell lung cancer treated with concurrent chemoradiotherapy

Frontiers in Cardiovascular Medicine2022-12-0218 citations

Toxicity and Survival After Intensity-Modulated Proton Therapy Versus Passive Scattering Proton Therapy for NSCLC.

2020-10-2234 citations

Perspectives on the model-based approach to proton therapy trials: A retrospective study of a lung cancer randomized trial.

2020-03-275 citations

Association of lung fluorodeoxyglucose uptake with radiation pneumonitis after concurrent chemoradiation for non-small cell lung cancer.

2017-05-119 citations

PRONTOX - proton therapy to reduce acute normal tissue toxicity in locally advanced non-small-cell lung carcinomas (NSCLC): study protocol for a randomised controlled trial.

2016-11-1515 citations

Bayesian randomized trial comparing intensity modulated radiation therapy versus passively scattered proton therapy for locally advanced non-small cell lung cancer.

Journal of Clinical Oncology2016-05-2034 citations

Normal-lung uptake of fluorodeoxyglucose, patient-reported symptoms, and clinician-rated radiation pneumonitis in patients with non-small cell lung cancer treated with chemoradiation.

Journal of Clinical Oncology2016-05-201 citations