Phentolamine Mesylate

DRUG7 trials

Conditions

CVA (Cerebrovascular Accident)Cardiovascular System DiseaseCerebral HemorrhageDrug-Related Side Effects and Adverse ReactionsHealthyIntracranial HemorrhagesObesityProstate Cancer

Early Phase 1

Sex Disparities in Hypoxic Vasodilation and Impact of Obesity

RecruitingNCT05219799

University of Missouri-ColumbiaHealthy, Obesity, Vasodilation

Start: 2023-03-14End: 2026-06-30Target: 72Updated: 2025-05-29

Phase 1

A Study of the Pharmacokinetic and Pharmacodynamic Responses in Healthy and Altered Human Cardiovascular Systems

TerminatedNCT03098680

Cambridge University Hospitals NHS Foundation TrustCardiovascular System Disease, Drug-Related Side Effects and Adverse Reactions

Start: 2017-04-24End: 2020-02-29Updated: 2021-03-22

Phase 2

Nerve-Sparing Radical Prostatectomy With or Without Nerve Grafting Followed by Standard Therapy for Erectile Dysfunction in Treating Patients With Localized Prostate Cancer

CompletedNCT00080808

M.D. Anderson Cancer CenterProstate Cancer

Start: 2001-08-31End: 2009-07-31Updated: 2012-07-30

Phase 4

Sympathetic Neurovascular Transduction: Role of Adrenergic Receptors and Sex Differences

RecruitingNCT05997732

University of AlbertaVasoconstriction, Vasodilation

Start: 2023-10-31End: 2027-12-01Target: 30Updated: 2026-01-08

Unknown Phase

Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage

CompletedNCT00226096

The George InstituteCerebral Hemorrhage, CVA (Cerebrovascular Accident), Intracranial Hemorrhages

Start: 2005-11-30End: 2007-09-30Updated: 2008-06-26

Reversing the Effects of 2% Lidocaine

CompletedNCT02861378

Dalhousie UniversitySoft Tissue Anaesthesia

Start: 2015-10-31End: 2016-04-30Updated: 2016-10-14

Sex Differences in Sympathetic Vascular Reactivity at High Altitude

CompletedNCT05525416

University of AlbertaVasoconstriction, Vasodilation

Start: 2022-07-28End: 2023-02-05Updated: 2024-09-19

2026-03-19

Effects of blood pressure lowering in relation to time in acute intracerebral haemorrhage: a pooled analysis of the four INTERACT trials.

2025-07-019 citations

Optimum Baseline Clinical Severity Scale Cut Points for Prognosticating Intracerebral Hemorrhage: INTERACT Studies

Stroke2023-11-2918 citations

Sudden onset severe epigastric pain in a man aged 48 years

Emergency Medicine Journal2022-09-201 citations

Sex differences in treatment, radiological features and outcome after intracerebral haemorrhage: Pooled analysis of Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage trials 1 and 2

European Stroke Journal2020-09-2127 citations

Utility-Weighted Modified Rankin Scale Scores for the Assessment of Stroke Outcome

Stroke2020-07-0935 citations

Infratentorial Intracerebral Hemorrhage

Stroke2019-03-2033 citations

Determinants of the high admission blood pressure in mild-to-moderate acute intracerebral hemorrhage

Journal of Hypertension2019-02-068 citations

Reversing the effects of 2% Lidocaine: A randomized controlled clinical trial.

2018-03-208 citations

Associations with health-related quality of life after intracerebral haemorrhage: pooled analysis of INTERACT studies

Journal of Neurology Neurosurgery & Psychiatry2016-10-2124 citations

Early blood pressure lowering in patients with intracerebral haemorrhage and prior use of antithrombotic agents: pooled analysis of the INTERACT studies

Journal of Neurology Neurosurgery & Psychiatry2016-05-1330 citations

Admission Heart Rate Predicts Poor Outcomes in Acute Intracerebral Hemorrhage

Stroke2016-05-1133 citations

Prognostic significance of delayed intraventricular haemorrhage in the INTERACT studies

Journal of Neurology Neurosurgery & Psychiatry2016-01-0824 citations

Rapid Blood Pressure Lowering According to Recovery at Different Time Intervals after Acute Intracerebral Hemorrhage: Pooled Analysis of the INTERACT Studies.

2015-03-2521 citations

Prognostic Significance of Perihematomal Edema in Acute Intracerebral Hemorrhage

Stroke2015-02-26150 citations

No Relationship of Lipid-Lowering Agents to Hematoma Growth

Stroke2015-02-069 citations

Higher mortality in patients with right hemispheric intracerebral haemorrhage: INTERACT1 and 2

Journal of Neurology Neurosurgery & Psychiatry2015-01-1418 citations

Clinical Prediction Algorithm (BRAIN) to Determine Risk of Hematoma Growth in Acute Intracerebral Hemorrhage

Stroke2014-12-12120 citations

Hematoma growth and outcomes in intracerebral hemorrhage: the INTERACT1 study.

2012-06-27204 citations

Randomized phase II trial evaluation of erectile function after attempted unilateral cavernous nerve-sparing retropubic radical prostatectomy with versus without unilateral sural nerve grafting for clinically localized prostate cancer.

2008-09-0240 citations

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