Phentolamine

DRUG9 trials

Conditions

Acute Coronary SyndromeAdrenergic Receptor Antagonist Adverse ReactionCA-AKI - Contrast-Associated Acute Kidney InjuryCoronary Artery DiseaseDiabetes Mellitus, Type 1EsmololFunctional Endoscopic Sinus SurgeryHealthy

Early Phase 1

Adrenergic System in Islet Transplantation

Active, not recruitingNCT03079921

University of PennsylvaniaHypoglycemia, Hypoglycemia Unawareness, Islet Cell Transplantation +1

Start: 2017-01-20End: 2025-12-31Updated: 2025-02-13

Sex Disparities in Hypoxic Sympatholysis and Impact of Obesity

Active, not recruitingNCT04436731

University of Missouri-ColumbiaHealthy, Obesity, Vasoconstriction +1

Start: 2020-12-09End: 2026-06-30Target: 104Updated: 2025-06-04

Phase 1

Role of Sympathetic Vasoconstriction on Insulin-Mediated Microvascular Recruitment and Glucose Uptake in Obesity

Active, not recruitingNCT03318094

Vanderbilt University Medical CenterHealthy, Insulin Resistance, Obesity

Start: 2017-10-24End: 2027-11-30Target: 36Updated: 2026-03-02

Phase 2

Efficacy of Phentolamine in Prevention of Contrast-Associated Acute Kidney Injury After Complex PCI

RecruitingNCT06286059

Helwan UniversityAcute Coronary Syndrome, Adrenergic Receptor Antagonist Adverse Reaction, CA-AKI - Contrast-Associated Acute Kidney Injury +1

Start: 2024-03-07End: 2025-01-31Target: 60Updated: 2024-03-18

Unknown Phase

The Effect of Alfa-Adrenergic Receptor Blockade on Insulin-Stimulated Forearm Glucose Uptake and Metabolism in Chronic Heart Failure

NCT00132106

Radboud University Medical CenterHeart Failure, Congestive

Start: 2005-08-31Updated: 2007-08-31

Comparison between Phentolamine and Nitroglycerin for Controlled Hypotension during Functional Endoscopic Sinus Surgery (FESS)

RecruitingPACTR201712002828410

Dina Mahmoud FakhrySurgery Hypotensive Anesthesia Anaesthesia

Start: 2017-11-25Target: 30Updated: 2026-01-27

Intravenous Labetalol vs Phentolamine for the Management of Severe Preeclampsia.

Not yet recruitingNCT06385600

Assiut UniversitySevere Pre-eclampsia

Start: 2024-05-20End: 2026-03-20Target: 200Updated: 2024-04-26

The Role of the Adrenergic System in Hypoglycaemia Induced Inflammatory Response in People With Type 1 Diabetes and People Without Type 1 Diabetes-RAID-II

Active, not recruitingNCT06422494

Radboud University Medical CenterDiabetes Mellitus, Type 1, Inflammation

Start: 2025-01-01End: 2025-10-31Target: 24Updated: 2025-07-24

Pre-operative Phentolamine Vs Intraoperative Esmolol Efficacy for Hypotensive Anesthesia in Functional Endoscopic Sinus Surgery

Not yet recruitingNCT06620991

Ain Shams UniversityEsmolol, Functional Endoscopic Sinus Surgery, Hypotensive Anesthesia +3