pertuzumab [Perjeta]

DRUG2 trials

Sponsors

Genentech, Inc., Hoffmann-La Roche

Conditions

Breast CancerMetastatic Breast Cancer

Phase 1

A Study of Trastuzumab Emtansine, Paclitaxel, and Pertuzumab in Patients With HER2-Positive, Locally Advanced or Metastatic Breast Cancer

CompletedNCT00951665

Genentech, Inc.Metastatic Breast Cancer

Start: 2009-08-31End: 2013-06-30Updated: 2016-06-24

Phase 3

Phase IIIb Study to Evaluate the Safety and Tolerability of Herceptin SC With Perjeta and Docetaxel in Patients With HER2-positive Advanced Breast Cancer

CompletedNCT02402712

Hoffmann-La RocheBreast Cancer

Start: 2015-05-06End: 2019-02-22Updated: 2019-09-06

Related Papers

Incidence and severity of anaphylaxis and hypersensitivity in trials of intravenous pertuzumab plus trastuzumab or the fixed-dose combination of pertuzumab and trastuzumab for subcutaneous injection for HER2-positive breast cancer.

2022-10-074 citations

Subcutaneous trastuzumab with pertuzumab and docetaxel in HER2-positive metastatic breast cancer: Final analysis of MetaPHER, a phase IIIb single-arm safety study

Breast Cancer Research and Treatment2021-03-2120 citations

Abstract P1-18-05: Subcutaneous trastuzumab and hyaluronidase-oysk with intravenous pertuzumab and docetaxel in HER2-positive advanced breast cancer: Final analysis of the phase IIIb, multicenter, open-label, single-arm MetaPHER study

Cancer Research2020-02-15

Subcutaneous trastuzumab (H SC) with intravenous pertuzumab (P IV) and docetaxel (D IV) in HER2-positive advanced breast cancer (BC): MetaPHER second interim analysis

Annals of Oncology2018-10-013 citations

Phase 1b/2a study of trastuzumab emtansine (T-DM1), paclitaxel, and pertuzumab in HER2-positive metastatic breast cancer

Breast Cancer Research2016-03-1547 citations

Abstract OT3-01-13: MetaPHER: A phase IIIb multicenter, open-label, single-arm safety study of subcutaneous trastuzumab, in combination with pertuzumab and docetaxel in patients with HER2-positive advanced breast cancer

Cancer Research2016-02-153 citations