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Peripheral blood collection

PROCEDURE10 trials

Sponsors

GlaxoSmithKline, University of Washington, Van Andel Research Institute, Chonbuk National University Hospital, Ruijin Hospital

Conditions

AMLAcute Myeloid LeukemiaCMMLCOPDChronic Myelomonocytic LeukemiaDiabetes Mellitus, Type 1HealthyHealthy Donors

Phase 1

Drug Concentration of Metformin According to Sampling Method
CompletedNCT03970434
Chonbuk National University HospitalHealthy
Start: 2019-05-30End: 2019-06-05Updated: 2019-06-13
Cabozantinib and Abiraterone With Checkpoint Inhibitor Immunotherapy in Metastatic Hormone Sensitive Prostate Cancer (CABIOS Trial)
CompletedNCT04477512
Washington University School of MedicineMetastatic Hormone Refractory Prostate Cancer
Start: 2021-02-19End: 2025-09-10Updated: 2025-11-12

Phase 3

Adjuvant Avelumab in Merkel Cell Cancer
Active, not recruitingNCT03271372
University of WashingtonStage IIIA Merkel Cell Carcinoma AJCC v8, Stage IIIB Merkel Cell Carcinoma AJCC v8, Stage III Merkel Cell Carcinoma AJCC v8
Start: 2017-12-19End: 2029-02-18Updated: 2026-06-15

Unknown Phase

Immune Profile in Subjects With New Onset Type 1 Diabetes
CompletedNCT02801942
GlaxoSmithKlineDiabetes Mellitus, Type 1
Start: 2016-07-25End: 2017-12-21Updated: 2019-02-27
Ascorbic Acid Levels in MDS, AML, and CMML Patients
CompletedNCT03526666
Van Andel Research InstituteAcute Myeloid Leukemia, AML, Chronic Myelomonocytic Leukemia +3
Start: 2017-11-01End: 2018-10-31Updated: 2019-10-03
Cell Free DNA in Mature B-cell Lymphoma
RecruitingNCT04088422
Ruijin HospitalMature B-Cell Lymphoma
Start: 2022-09-28End: 2026-12-31Target: 320Updated: 2023-02-24
Selected Immunological Indicators and Microbiota in Patients With Premature Birth and Preeclampsia
RecruitingNCT06281262
General University Hospital, PraguePreeclampsia, Preterm Birth
Start: 2023-06-30End: 2025-03-30Target: 100Updated: 2024-03-01
Validation of the MaiRa Preeclampsia Test for Screening Early/Late Preeclampsia in First and Second Trimesters
RecruitingNCT06716242
iPremomPreeclampsia (PE)
Start: 2024-12-02End: 2027-02-01Target: 7473Updated: 2026-05-15
CAR-NK Cells Production and Expansion From Patients With Lympho or Myeloproliferative Disorders and From Healthy Donors
RecruitingNCT06727383
European Institute of OncologyHealthy Donors, Lymphoproliferative Disorders, Myeloproliferative Diseases
Start: 2022-12-21End: 2025-12-21Target: 140Updated: 2024-12-10
Identification of Diagnostic and Prognostic Biomarkers in the Pathological Continuum of Bronco Chronic Obstructive Pulmonary Disease, Idiopathic Pulmonary Fibrosis and Pulmonary Neoplasia
RecruitingNCT07707245
Fondazione Don Carlo Gnocchi ETSCOPD, Idiopathic Pulmonary Fibrosis (IPF), Lung Cancer
Start: 2026-04-22End: 2028-10-30Target: 120Updated: 2026-07-16

Related Papers

ADAM trial: A multicenter, randomized, double-blinded, placebo-controlled, phase 3 trial of adjuvant avelumab (anti-PD-L1 antibody) in patients with Merkel cell carcinoma and lymph node metastases.
Journal of Clinical Oncology2026-06-03
O-089 Maternal plasma cell-free RNA as a liquid biopsy for first-trimester screening of early and late-onset preeclampsia
Human Reproduction2025-06-01
A phase 1b study of cabozantinib and nivolumab with abiraterone (CABIOS) in metastatic castration-sensitive prostate cancer (mCSPC): Updated safety, efficacy, and immunologic findings.
Journal of Clinical Oncology2025-02-10
LAMP1 targeting of the large T antigen of Merkel cell polyomavirus results in potent CD4 T cell responses and tumor inhibition
Frontiers in Immunology2023-08-3012 citations
CABIOS trial: A phase Ib study of cabozantinib and nivolumab in combination with abiraterone in patients (pts) with metastatic hormone sensitive prostate cancer (mHSPC).
Journal of Clinical Oncology2023-06-013 citations
Circulating tumor DNA as a predictive biomarker in Merkel cell carcinoma
Journal of the American Academy of Dermatology2022-03-1917 citations
A phase 1b clinical trial of cabozantinib (CABO) and abiraterone (ABI) with checkpoint inhibitor immunotherapy (CPI) in metastatic hormone-sensitive prostate cancer (mHSPC) (CABIOS Trial).
Journal of Clinical Oncology2022-02-164 citations
Avelumab in patients with previously treated metastatic Merkel cell carcinoma: long-term data and biomarker analyses from the single-arm phase 2 JAVELIN Merkel 200 trial
Journal for ImmunoTherapy of Cancer2020-05-01193 citations
ADAM trial: A multicenter, randomized, double-blinded, placebo-controlled, phase 3 trial of adjuvant avelumab (anti-PD-L1 antibody) in merkel cell carcinoma patients with clinically detected lymph node metastases; NCT03271372.
Journal of Clinical Oncology2018-05-2011 citations