PD-1 knockout engineered T cells

BIOLOGICAL2 trials

Sponsors

The First Affiliated Hospital of Guangdong Pharmaceutical University, Central South University

Conditions

Advanced Esophageal CancerAdvanced Hepatocellular Carcinoma

Phase 1

CAR T and PD-1 Knockout Engineered T Cells for Esophageal Cancer

The First Affiliated Hospital of Guangdong Pharmaceutical UniversityAdvanced Esophageal Cancer

Start: 2018-09-28End: 2021-09-28Target: 20Updated: 2018-10-16

TACE Combined With PD-1 Knockout Engineered T Cell in Advanced Hepatocellular Carcinoma.

Central South UniversityAdvanced Hepatocellular Carcinoma

Start: 2019-06-20End: 2024-12-31Target: 10Updated: 2023-02-09

Related Papers

Phase I clinical trial using a unique immunotherapeutic combination of MUC1-targeted CAR-T cells with PD-1-knockout in the treatment of patients with advanced esophageal cancer.

Journal of Clinical Oncology2023-06-017 citations