OTO-104

DRUG9 trials

Sponsors

Otonomy, Inc.

Conditions

Cisplatin Induced Hearing LossMeniere DiseaseMeniere's Disease

Phase 2

OTO-104 for the Treatment of Meniere's Disease

CompletedNCT01412177

Otonomy, Inc.Meniere's Disease

Start: 2013-11-30End: 2015-04-30Updated: 2015-09-03

A 1-Year Safety Study of OTO-104 in Subjects With Unilateral Meniere's Disease Located in United Kingdom

CompletedNCT02265393

Otonomy, Inc.Meniere's Disease

Start: 2014-10-31End: 2016-05-31Updated: 2017-08-18

Open Label Study of OTO-104 in Subjects With Meniere's Disease

TerminatedNCT02740387

Otonomy, Inc.Meniere's Disease

Start: 2016-06-30End: 2017-09-30Updated: 2017-09-15

Study of OTO-104 in Subjects at Risk From Cisplatin-Induced Hearing Loss

TerminatedNCT02997189

Otonomy, Inc.Cisplatin Induced Hearing Loss

Start: 2016-11-15End: 2017-09-26Updated: 2020-09-16

Phase 3

Study of OTO-104 in Subjects With Unilateral Meniere's Disease

CompletedNCT02612337

Otonomy, Inc.Meniere's Disease

Start: 2015-10-27End: 2017-07-18Updated: 2023-01-12

A 6-Month Extension Study of OTO-104 in Meniere's Disease

TerminatedNCT02706730

Otonomy, Inc.Meniere's Disease

Start: 2016-02-29End: 2017-09-30Updated: 2022-12-14

Study of OTO-104 in Subjects With Unilateral Meniere's Disease

TerminatedNCT02717442

Otonomy, Inc.Meniere's Disease

Start: 2016-03-21End: 2017-09-15Updated: 2023-01-13

A 6-Month Extension Study of OTO-104 in Meniere's Disease

TerminatedNCT02768662

Otonomy, Inc.Meniere's Disease

Start: 2016-08-31End: 2017-09-30Updated: 2023-01-20

Phase 3 Study of OTO-104 in Subjects With Unilateral Meniere's Disease

CompletedNCT03664674

Otonomy, Inc.Meniere Disease

Start: 2018-08-27End: 2020-12-22Updated: 2022-12-07

Related Papers

Feasibility and Safety of Intratympanic Administration of Sustained‐Exposure Dexamethasone Thermosensitive Gel (OTO‐104) for Prevention of Cisplatin‐Induced Hearing Loss in Children: A Multisite Phase 2 Randomized Clinical Trial

Pediatric Blood & Cancer2025-03-24

Efficacy of Intratympanic OTO-104 for the Treatment of Ménière's Disease: The Outcome of Three Randomized, Double-Blind, Placebo-Controlled Studies

Otology & Neurotology2023-04-2215 citations