Oral treprostinil
Sponsors
United Therapeutics, Brigham and Women's Hospital, Stanford University
Conditions
CalcinosisHeart Failure With Preserved Ejection FractionPAHPulmonary Arterial HypertensionPulmonary FibrosisPulmonary HypertensionPulmonary Hypertension Associated With HFpEFPulmonary Hypertension Associated With Sickle Cell Disease
Early Phase 1
Phase 2
Safety, Tolerability, and Pharmacokinetics of Oral Treprostinil in Pediatric PAH Patients Aged 7 to 17 Years
CompletedNCT02276872
Start: 2014-12-18End: 2017-07-20Updated: 2025-03-30
Oral Treprostinil in Subjects With Pulmonary Hypertension Associated With Pulmonary Fibrosis
WithdrawnNCT02603068
Start: 2016-02-29End: 2018-07-31Updated: 2016-02-09
Safety and Efficacy of Oral Treprostinil in the Treatment of Calcinosis in Patients With Systemic Sclerosis
CompletedNCT02663895
Start: 2016-10-31End: 2020-05-13Updated: 2021-06-10
Safety of Transition From Selexipag to Remodulin® Then Oral Treprostinil in Symptomatic Adult PAH
WithdrawnNCT03016468
Start: 2017-05-31End: 2018-09-30Updated: 2017-04-11
Phase 3
An Open-Label Extension Trial of UT-15C Sustained-release (SR) in Subjects With Pulmonary Arterial Hypertension
CompletedNCT01027949
Start: 2007-01-16End: 2020-02-12Updated: 2021-05-10
Study to Compare Triple Therapy (Oral Treprostinil, Ambrisentan, and Tadalafil) With Dual Therapy (Ambrisentan, Tadalafil, and Placebo) in Subjects With Pulmonary Arterial Hypertension
WithdrawnNCT02999906
Start: 2017-10-31End: 2022-06-30Updated: 2017-11-01
Oral Treprostinil in Subjects With Pulmonary Hypertension Associated With Heart Failure With Preserved Ejection Fraction
TerminatedNCT03037580
Start: 2017-08-15End: 2019-12-03Updated: 2020-11-10
Open-label Extension of Oral Treprostinil in Subjects With PH Associated With HFpEF
TerminatedNCT03043651
Start: 2018-01-30End: 2020-03-02Updated: 2020-10-22
Study to Evaluate Efficacy and Safety of Oral Treprostinil in Subjects With Pulmonary Hypertension (PH) Associated With Sickle Cell Disease (SCD)
WithdrawnNCT03055234
Start: 2017-06-30End: 2022-12-31Updated: 2017-04-11