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Oral tranexamic acid

DRUG10 trials

Sponsors

Baylor College of Medicine, Rush University Medical Center, Universidad Autonoma de Nuevo Leon, Centro Dermatológico Dr. Ladislao de la Pascua, Ain Shams University

Conditions

AnesthesiaArthroplastyBlood ClotBlood LossBlood Loss After Primary Total Joint ArthroplastyChloasmaCoronary Artery DiseaseKnee Osteoarthritis

Early Phase 1

Comparison of Intradermal Microinjections of Tanexamic Acid and Oral Tranexamic Acid in the Management of Melasma.
CompletedNCT07280234
Hayat Abad Medical Complex, PeshawarMelasma
Start: 2024-11-14End: 2025-05-15Updated: 2025-12-12

Phase 2

Oral Tranexamic Acid vs. Oral Aminocaproic Acid to Reduce Blood Loss and Transfusion After Total Knee Replacement.
CompletedNCT03365999
Universidad Autonoma de Nuevo LeonBlood Clot, Blood Loss, Knee Osteoarthritis +1
Start: 2017-10-15End: 2019-07-01Updated: 2019-07-30
Evaluation of the Efficacy of Oral Tranexamic Acid and Glutathione-assisted Microneedling in Treatment of Melasma
Not yet recruitingNCT07448415
Assiut UniversityMelasma
Start: 2026-02-01End: 2027-04-01Target: 42Updated: 2026-03-04

Phase 3

Oral and Topical Tranexamic Acid for the Treatment of Melasma
NCT03585179
Centro Dermatológico Dr. Ladislao de la PascuaChloasma, Melanosis, Melasma
Start: 2018-08-01End: 2020-06-01Target: 120Updated: 2018-07-16
Effects of Oral Tranexamic Acid on Short Term Postoperative Outcomes Following Total Shoulder Arthroplasty
RecruitingNCT06902714
University of Alabama at BirminghamShoulder Arthroplasty
Start: 2026-04-20End: 2030-12-01Target: 60Updated: 2026-04-28

Phase 4

Tranexamic Acid in Functional Endoscopic Sinus Surgery
CompletedNCT05686005
Ain Shams UniversityAnesthesia
Start: 2022-12-03End: 2023-04-30Updated: 2023-05-03
Postoperative Oral Tranexamic Acid in Patients Undergoing Primary Total Joint Arthroplasty
RecruitingNCT06832878
Mayo ClinicArthroplasty
Start: 2026-06-01End: 2027-06-01Target: 101Updated: 2026-08-10
Oral Versus Intravenous Tranexamic Acid in Off-Pump Coronary Artery Bypass Surgery
Not yet recruitingNCT07740330
Clinique Saint-LucCoronary Artery Disease, Perioperative Bleeding
Start: 2026-10-01End: 2028-07-01Target: 160Updated: 2026-07-31

Unknown Phase

Tranexamic Acid (TA) vs Combined Oral Contraceptive (COCP) Pilot Study
CompletedNCT01428713
Baylor College of MedicineMenorrhagia
Start: 2011-08-31End: 2013-06-30Updated: 2016-08-10
Oral vs. Intravenous TXA Study Proposal: TJA
CompletedNCT02233101
Rush University Medical CenterBlood Loss After Primary Total Joint Arthroplasty, Need for Blood Transfusion After Total Joint Arthroplasty
Start: 2014-06-30End: 2015-08-31Updated: 2017-11-28