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Optison

DRUG11 trials

Sponsors

St. Jude Children's Research Hospital, University Hospital, Basel, Switzerland, University of Nebraska, GE Healthcare, University of Michigan

Conditions

Abdominal NeoplasmsCarotid Artery DiseaseCarotid StenosisCoronary Artery DiseaseCoronary StenosisCrohn's DiseaseHeart TransplantationLymphedema Arm

Phase 1

Determination of a Safe Dose of Optison in Pediatric Patients With Solid Tumors
CompletedNCT00186953
St. Jude Children's Research HospitalAbdominal Neoplasms, Pelvic Neoplasms
Start: 2002-06-30End: 2004-08-31Updated: 2011-09-20
Assessing Myocardial Blood Flow and Blood Flow Reserve by Transoesophageal Echocardiography (TEE)
WithdrawnNCT00286559
University Hospital, Basel, SwitzerlandCoronary Artery Disease
Start: 2006-08-31End: 2008-12-31Updated: 2015-03-25
Contrast-Enhanced Ultrasound in Human Crohn's Disease
WithdrawnNCT02061163
University of MichiganCrohn's Disease
Start: 2015-02-28End: 2018-01-31Updated: 2015-06-15
CeVUS With Intravesical Administration of OPTISON TM (Trademark) in Children
CompletedNCT02204917
Kassa DargeVesico-Ureteral Reflux
Start: 2014-07-31End: 2017-03-31Updated: 2018-11-27
Contrast-Enhanced Ultrasound and Shear Wave Elastography for the Treatment of Lymphedema
CompletedNCT05613946
Mayo ClinicLymphedema Arm
Start: 2022-12-15End: 2024-06-30Updated: 2024-08-21

Phase 2

Dose-Finding, Feasibility Study of Optison in Contrast Enhanced U/S for the Detection of Carotid Artery Disease
TerminatedNCT01394926
GE HealthcareCarotid Artery Disease
Start: 2011-06-30End: 2012-06-30Updated: 2014-05-02
Two and Three Dimensional Contrast-enhanced Ultrasound for Screening of Renal Cell Carcinoma Recurrence Following Cryoablation
CompletedNCT02440334
Thomas Jefferson UniversityRenal Cell Carcinoma
Start: 2015-04-23End: 2018-06-21Updated: 2025-05-04

Phase 4

IRB 14-009240, Does CEUS Positively Influence Selection of Biopsy Sites When Evaluating Transplant Kidneys?
CompletedNCT02625428
Mayo ClinicTransplantation, Kidney
Start: 2015-11-30End: 2019-12-31Updated: 2020-03-02
Study to Determine Safety and Dosage of OPTISON in Pediatric Participants
CompletedNCT03740997
GE HealthcareSuspected or Known Structural or Functional Cardiac Abnormality, Transthoracic Echocardiography
Start: 2020-12-01End: 2023-03-30Updated: 2024-05-17

Unknown Phase

Detection of Coronary Stenosis With Intravenous Microbubbles
WithdrawnNCT00580580
University of NebraskaCarotid Stenosis, Coronary Stenosis, Myocardial Reperfusion
Start: 2012-02-29End: 2014-03-31Updated: 2024-09-23
Myocardial Perfusion Echocardiography to Detect Human Heart Transplant Rejection
TerminatedNCT02300870
Brigham and Women's HospitalHeart Transplantation
Start: 2015-01-31End: 2019-12-31Updated: 2023-07-27