Ondansetron (Zofran)

DRUG8 trials

Sponsors

National Institute on Alcohol Abuse and Alcoholism (NIAAA), United States Army Institute of Surgical Research, Makassed General Hospital, Assiut University, Hafiz Muhammad Hamza

Conditions

AlcoholismCesarean SectionItchingPONVPostoperative Nausea and Vomiting (PONV)PruritusSpinal Anaesthesia Induced Hypotension

Phase 1

Chewing Gum vs. Ondansetron as Rescue Treatment for PONV in Female Patients

Active, not recruitingNCT07201883

Makassed General HospitalPostoperative Nausea and Vomiting (PONV)

Start: 2025-08-22End: 2026-02-28Target: 90Updated: 2025-10-01

Phase 2

Ondansetron Treatment for Alcoholism

CompletedNCT00000443

National Institute on Alcohol Abuse and Alcoholism (NIAAA)Alcoholism

End: 2000-04-30Updated: 2005-06-24

Combined Pharmacotherapies for Alcoholism (Naltrexone/Ondansetron)

CompletedNCT00027079

National Institute on Alcohol Abuse and Alcoholism (NIAAA)Alcoholism

Start: 2001-09-30End: 2004-08-31Target: 360Updated: 2007-12-10

Role of Ondansetron in Spinal Anaesthesia Induced Hypotension

Not yet recruitingNCT06727201

Assiut UniversitySpinal Anaesthesia Induced Hypotension

Start: 2025-01-01End: 2027-02-01Target: 160Updated: 2024-12-10

Phase 4

Ondansetron vs. Dexamethasone for Postoperative Nausea

CompletedNCT06886230

Hafiz Muhammad HamzaPostoperative Nausea and Vomiting (PONV)

Start: 2025-03-20End: 2025-06-11Updated: 2025-06-17

Aprepitant to Improve Same Day Discharge for TKA

Not yet recruitingNCT07639723

Endeavor HealthPONV

Start: 2026-07-01End: 2027-08-01Target: 350Updated: 2026-06-10

Unknown Phase

Post Burn Pruritus Study in Patients Undergoing Wound Healing

CompletedNCT00137202

United States Army Institute of Surgical ResearchItching

Start: 2005-06-30End: 2006-05-31Updated: 2008-07-28

Ondansetron vs Ondansetron Plus Dexamethasone for Relieving Intrathecal Morphine Side Effects After C-section

CompletedNCT02793843

Makassed General HospitalCesarean Section, Pruritus

Start: 2016-06-30End: 2017-07-30Updated: 2017-11-06