Oliceridine

DRUG18 trials

Conditions

Acute PainAdverse Drug EventAnalgeisaAnalgesiaAnesthesiaBurnsCerebellopontine Angle TumorChronic Postsurgical Pain

Phase 3

Study of Oliceridine (TRV130) for the Treatment of Moderate to Severe Acute Pain After Bunionectomy

CompletedNCT02815709

Trevena Inc.Acute Pain

Start: 2016-05-31End: 2017-01-31Updated: 2020-09-25

Study of Oliceridine (TRV130) for the Treatment of Moderate to Severe Acute Pain After Abdominoplasty

CompletedNCT02820324

Trevena Inc.Acute Pain

Start: 2016-05-31End: 2017-01-31Updated: 2020-10-23

Phase 4

Intravenous Oliceridine and Opioid-related Complications

CompletedNCT04979247

The Cleveland ClinicMajor Surgery

Start: 2021-09-15End: 2024-01-10Updated: 2026-05-14

Oliceridine in Patients With Acute Burn Injuries

CompletedNCT05465226

University of TennesseeAcute Pain, Adverse Drug Event, Burns +2

Start: 2023-04-01End: 2023-10-24Updated: 2023-10-26

Effect of Oliceridine Analgesia on Postoperative Nause and Vomiting

CompletedNCT06411665

Peking University First HospitalLaparoscopic Colorectal Surgery, Morphine, Oliceridine +2

Start: 2024-07-02End: 2025-04-14Updated: 2026-06-24

To Evaluate the Efficacy and Safety of Tegileridine and Oliceridine Injections in the Treatment of Postoperative Pain

CompletedNCT06458400

Yuwei QiuAnalgesia

Start: 2024-07-03End: 2024-10-06Updated: 2025-01-01

The Effect of Oliceridine Patient-Controlled Intravenous Analgesia on Postoperative Chronic Pain After Video-Assisted Thoracoscopic Lobectomy

Enrolling by invitationNCT07018375

Tianjin Medical University General HospitalChronic Postsurgical Pain

Start: 2026-01-06End: 2027-04-30Target: 320Updated: 2026-07-09

Oliceridine on Postoperative Nausea and Vomiting in Gynecological Laparoscopic Surgery

CompletedNCT07026162

YanYing XiaoGynecologic Surgical Procedures, Laparoscopy, Postoperative Nausea and Vomiting (PONV)

Start: 2025-07-21End: 2026-02-25Updated: 2026-06-09

Dexmedetomidine-Enhanced PCIA After Lobectomy in Nicotine-Dependent Patients

WithdrawnNCT07306702

Shenyang Sixth People's HospitalPostoperative Pain Management

Start: 2026-06-01End: 2027-05-30Updated: 2026-04-13

Oliceridine vs Sufentanil for Cough During Anesthesia Induction

Not yet recruitingNCT07660380

Shiyou WeiAnesthesia, Cough

Start: 2026-06-22End: 2026-07-01Target: 62Updated: 2026-06-23

Unknown Phase

Clinical Study of G Protein Biased Μ - Opioid Receptor Agonist Oliceridine for Optimizing Postoperative Analgesia Under General Anesthesia

Not yet recruitingNCT06668298

Henan Provincial People's HospitalOld Age

Start: 2024-11-30End: 2025-06-30Target: 150Updated: 2024-10-31

Comparison of the Analgesic Effect of Oliceridine Versus Morphine or Sufentanil for Postoperative Analgesia in Lumbar Surgeries: a Randomized Control Trial

RecruitingNCT06990893

Anqing Municipal HospitalMorphine, Oliceridine, Safety +2

Start: 2025-06-01End: 2026-10-01Target: 90Updated: 2026-06-01

Analgesic Effect and Safety of Oliceridine and Oxycodone in Vitrectomy

Not yet recruitingNCT07097038

Henan Provincial People's HospitalVitrectomy

Start: 2025-07-31End: 2026-07-31Target: 120Updated: 2025-07-31

Efficacy of Oxalidine and Sufentanil in Strabismus Correction

Not yet recruitingNCT07112157

Henan Provincial People's HospitalStrabismus Surgery

Start: 2025-08-31End: 2026-08-31Target: 290Updated: 2025-08-08

Respiratory Safety of Oliceridine During Sedated Gastrointestinal Endoscopy

CompletedNCT07187765

Shiyou WeiGastrointestinal Endoscopy, Hypoxemia During Surgery

Start: 2025-09-22End: 2025-12-01Updated: 2026-01-05

Effects and Safety of Oliceridine in Anesthesia Induction:A Randomised Controlled Trial

CompletedNCT07372209

Tangshan Maternal and Child Health HospitalGeneral Anesthetic, Gynecological Laparoscopic Surgery, Intubation

Start: 2025-10-01End: 2025-12-31Updated: 2026-01-28

Oliceridine Versus Sufentanil for Postoperative Nausea in Cerebellopontine Angle Surgery

RecruitingNCT07479446

Xuanwu Hospital, BeijingCerebellopontine Angle Tumor, Microvascular Decompression Surgery, PONV +1

Start: 2026-03-25End: 2027-09-30Target: 174Updated: 2026-05-22

Comparison of the Efficacy and Safety of Oliceridine and Sufentanil in Patients Undergoing Outpatient Hysteroscopy

CompletedNCT07713134

Tangshan Maternal and Child Health HospitalAnalgeisa, Hysteroscopy

Start: 2025-08-01End: 2026-06-30Updated: 2026-07-20

Related Papers

Comparison of hemodynamic responses to endotracheal intubation with oliceridine and sufentanil during induction: a randomized controlled trial

BMC Anesthesiology2026-04-23

Oliceridine for postoperative pain and opioid-related complications: The intravenous oliceridine and opioid-related complications (VOLITION) prospective cohort study.

2025-05-292 citations

APOLLO-2: A Randomized, Placebo and Active-Controlled Phase III Study Investigating Oliceridine (TRV130), a G Protein-Biased Ligand at the μ-Opioid Receptor, for Management of Moderate to Severe Acute Pain Following Abdominoplasty.

2019-06-24116 citations

APOLLO-1: a randomized placebo and active-controlled phase III study investigating oliceridine (TRV130), a G protein-biased ligand at the µ-opioid receptor, for management of moderate-to-severe acute pain following bunionectomy.

2019-03-11103 citations