Natural history

OTHER8 trials

Sponsors

Ludwig-Maximilians - University of Munich, Virginia Commonwealth University, Emily de los Reyes, LYSOGENE, Monash University

Conditions

Batten DiseaseCLN1 DiseaseCLN10 DiseaseCLN11 DiseaseCLN12 DiseaseCLN13 DiseaseCLN14 DiseaseCLN2 Disease

Phase 1

Neural Mechanisms of Immersive Virtual Reality in Chronic Pain

Active, not recruitingNCT04851301

University of Maryland, BaltimorePain, Virtual Reality, Placebo +1

Start: 2021-11-01End: 2026-11-30Updated: 2026-02-27

Unknown Phase

Natural History in CCFDN and IBM Syndromes

CompletedNCT01902940

Ludwig-Maximilians - University of MunichInclusion Body Myositis, Sporadic, Inclusion Body Myopathy, Autosomal-recessive, Inclusion Body Myopathy, Autosomal-dominant +1

Start: 2013-06-30End: 2013-10-31Updated: 2015-09-01

Trial Readiness and Endpoint Assessment in Congenital Myotonic Dystrophy

CompletedNCT03059264

Virginia Commonwealth UniversityCongenital Myotonic Dystrophy

Start: 2016-12-14End: 2025-01-27Updated: 2025-03-11

Natural History of Neuronal Ceroid Lipofuscinosis, Batten's CLN6 Diseae

Active, not recruitingNCT03285425

Emily de los ReyesBatten Disease, CLN6

Start: 2017-01-31End: 2026-12-31Target: 30Updated: 2025-07-30

Interviews and Video Capture in Patients With GM1 Gangliosidosis

CompletedNCT04310163

LYSOGENEGM1 Gangliosidosis

Start: 2020-04-20End: 2023-05-05Updated: 2023-06-08

A Natural History Study to TRACK Brain and Spinal Cord Changes in Individuals with Friedreich Ataxia (TRACK-FA)

Active, not recruitingNCT04349514

Monash UniversityFriedreich Ataxia

Start: 2021-02-10End: 2025-10-31Target: 300Updated: 2024-11-27

Natural History and Longitudinal Clinical Assessments in NCL / Batten Disease, the International DEM-CHILD Database

RecruitingNCT04613089

Universitätsklinikum Hamburg-EppendorfNeuronal Ceroid Lipofuscinosis, Batten Disease, CLN1 Disease +12

Start: 2020-04-08End: 2050-04-08Target: 500Updated: 2021-10-29

Pancreatic Disease Burden in Older Adults (1990-2040)

CompletedNCT07177599

Changhai HospitalPancreatic Cancer, Pancreatitis

Start: 1990-01-01End: 2025-09-11Updated: 2025-09-17

Related Papers

Automated Deep Learning-based Segmentation of the Dentate Nucleus Using Quantitative Susceptibility Mapping MRI.

2025-11-01

Neuroimaging Biomarkers for Friedreich Ataxia: A Cross‐Sectional Analysis of the <scp>TRACK</scp>‐<scp>FA</scp> Study

Annals of Neurology2025-03-223 citations

A natural history study to track brain and spinal cord changes in individuals with Friedreich’s ataxia: TRACK-FA study protocol

PLoS ONE2022-11-2117 citations

Ongoing retinal degeneration despite intraventricular enzyme replacement therapy with cerliponase alfa in late-infantile neuronal ceroid lipofuscinosis type 2 (CLN2 disease)

British Journal of Ophthalmology2022-06-3019 citations

Natural History Studies in NCL and Their Expanding Role in Drug Development: Experiences From CLN2 Disease and Relevance for Clinical Trials.

2022-02-0818 citations