Metoprolol tartrate

DRUG10 trials

Sponsors

Vanderbilt University, The George Institute, Creighton University, University of Chicago, Corcept Therapeutics

Conditions

Angina (Stable)Atrial FibrillationCVA (Cerebrovascular Accident)Cerebral HemorrhageCoronary Arterial Disease (CAD)Coronary Computed Tomography AngiographyHealthyHeart Diseases

Phase 1

Treatment of Supine Hypertension in Autonomic Failure

CompletedNCT00223717

Vanderbilt UniversityHypertension

Start: 2001-01-31End: 2017-01-31Updated: 2017-10-13

Study in Healthy Subjects to Determine the Effect of Relacorilant on Exposure to Probe Substrates for Cytochrome P450s

CompletedNCT03457597

Corcept TherapeuticsHealthy

Start: 2018-03-06End: 2018-04-28Updated: 2018-05-17

Phase 2

Heart Rate Control Before Cardiac Computed Tomography in Adults for the Evaluation of Coronary Artery Disease

Enrolling by invitationNCT07268170

Gødstrup HospitalCoronary Arterial Disease (CAD), Ischemic Heart Disease (IHD)

Start: 2025-12-15End: 2028-09-30Target: 350Updated: 2025-12-17

Phase 3

Metoprolol to Reduce Perioperative Myocardial Injury

CompletedNCT03138603

University of ChicagoHeart Diseases

Start: 2016-12-01End: 2023-08-29Updated: 2026-01-28

Phase 4

Black Education and Treatment of Hypertension (BEAT HTN)

CompletedNCT00661895

Creighton UniversityHypertension

Start: 2005-08-31End: 2009-11-30Updated: 2012-12-04

Rate Control in Atrial Fibrillation

Creighton UniversityAtrial Fibrillation

Start: 2016-12-31End: 2017-09-30Target: 20Updated: 2016-06-16

Efficacy and Safety of Metoprolol Tartrate Tablets Combined With Chinese Traditional Medicine on Premature Ventricular Complex.

CompletedNCT05008250

Xuanwu Hospital, BeijingPremature Ventricular Contraction

Start: 2014-01-31End: 2016-08-31Updated: 2021-08-17

Heart Rate Controller in Computed Tomography Coronary Angiography

Mahidol UniversityCoronary Computed Tomography Angiography, Heart Rate

Start: 2021-01-30End: 2022-06-30Target: 246Updated: 2022-05-17

Effect of Beta-blockers on Coronary Flow and Resistance in Patients With ANOCA

RecruitingNCT06864234

VZW Cardiovascular Research Center AalstAngina (Stable), Coronary Arterial Disease (CAD), Microvascular Circulation

Start: 2025-07-03End: 2025-12-31Target: 46Updated: 2025-07-14

Unknown Phase

Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage

CompletedNCT00226096

The George InstituteCerebral Hemorrhage, CVA (Cerebrovascular Accident), Intracranial Hemorrhages

Start: 2005-11-30End: 2007-09-30Updated: 2008-06-26

Related Papers

Systolic Blood Pressure Trajectory and Outcomes in Acute Intracerebral Hemorrhage: Pooled Analysis of the 4 INTERACT and ATACH-II Clinical Trials.

2026-03-19

Effects of blood pressure lowering in relation to time in acute intracerebral haemorrhage: a pooled analysis of the four INTERACT trials.

2025-07-019 citations

Optimum Baseline Clinical Severity Scale Cut Points for Prognosticating Intracerebral Hemorrhage: INTERACT Studies

Stroke2023-11-2918 citations

Sudden onset severe epigastric pain in a man aged 48 years

Emergency Medicine Journal2022-09-201 citations

Sex differences in treatment, radiological features and outcome after intracerebral haemorrhage: Pooled analysis of Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage trials 1 and 2

European Stroke Journal2020-09-2127 citations

Utility-Weighted Modified Rankin Scale Scores for the Assessment of Stroke Outcome

Stroke2020-07-0935 citations

Infratentorial Intracerebral Hemorrhage

Stroke2019-03-2033 citations

Determinants of the high admission blood pressure in mild-to-moderate acute intracerebral hemorrhage

Journal of Hypertension2019-02-068 citations

Associations with health-related quality of life after intracerebral haemorrhage: pooled analysis of INTERACT studies

Journal of Neurology Neurosurgery & Psychiatry2016-10-2124 citations

Early blood pressure lowering in patients with intracerebral haemorrhage and prior use of antithrombotic agents: pooled analysis of the INTERACT studies

Journal of Neurology Neurosurgery & Psychiatry2016-05-1330 citations

Admission Heart Rate Predicts Poor Outcomes in Acute Intracerebral Hemorrhage

Stroke2016-05-1133 citations

Prognostic significance of delayed intraventricular haemorrhage in the INTERACT studies

Journal of Neurology Neurosurgery & Psychiatry2016-01-0824 citations

Rapid Blood Pressure Lowering According to Recovery at Different Time Intervals after Acute Intracerebral Hemorrhage: Pooled Analysis of the INTERACT Studies.

2015-03-2521 citations

Prognostic Significance of Perihematomal Edema in Acute Intracerebral Hemorrhage

Stroke2015-02-26150 citations

No Relationship of Lipid-Lowering Agents to Hematoma Growth

Stroke2015-02-069 citations

Higher mortality in patients with right hemispheric intracerebral haemorrhage: INTERACT1 and 2

Journal of Neurology Neurosurgery & Psychiatry2015-01-1418 citations

Clinical Prediction Algorithm (BRAIN) to Determine Risk of Hematoma Growth in Acute Intracerebral Hemorrhage

Stroke2014-12-12120 citations

Hematoma growth and outcomes in intracerebral hemorrhage: the INTERACT1 study.

2012-06-27204 citations

Intensive blood pressure reduction in acute cerebral haemorrhage trial (INTERACT): a randomised pilot trial.

2008-04-07520 citations