Methimazole

DRUG18 trials

Conditions

Atherosclerosis of ArteryDermatomyositisDrug WithdrawalGlioblastomaGliomaGraves DiseaseGraves OphthalmopathyGraves' Disease

Early Phase 1

Inducing a Hypothyroxinemic State in Patients With Recurrent Glioblastoma or Gliosarcoma

WithdrawnNCT05017610

Emory UniversityRecurrent Glioblastoma, Recurrent Gliosarcoma

Start: 2021-10-20End: 2022-10-14Updated: 2022-12-02

Phase 1

Rituximab in the Treatment of Graves' Disease

CompletedNCT00150111

Odense University HospitalGraves´ Disease, Thyroid Associated Ophthalmopathy

Start: 2003-06-30End: 2006-10-31Target: 20Updated: 2006-10-06

Phase 2

Methimazole to Treat Polymyositis and Dermatomyositis

CompletedNCT00001421

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)Dermatomyositis, Polymyositis

Start: 1995-06-30End: 2001-04-30Target: 20Updated: 2008-03-04

Methimazole in Patients With Progressive Glioblastoma

SuspendedNCT05607407

Case Comprehensive Cancer CenterGlioblastoma, Glioma

Start: 2023-01-30End: 2026-09-01Target: 19Updated: 2026-08-17

Phase 2 Study to Assess Efficacy & Safety of WP1302 Prevent Relapse of MMI w/Draw in Subj. w/ Graves' dz

SuspendedNCT06240455

Worg Biotherapeutics Inc.Graves Disease

Start: 2026-03-31End: 2030-09-30Target: 176Updated: 2025-05-08

Impact of Vitamin D Therapy on Thyroid Function and Antibody Levels in Pediatric Graves' Disease

Active, not recruitingNCT07369063

Northwell HealthGraves Disease, Graves' Disease, Hyperthyroidism

Start: 2025-08-25End: 2026-10-29Target: 30Updated: 2026-10-23

Phase 3

A Conservative vs an Ablative Approach for Treatment of Hyperthyroidism in Patients With Graves' Orbitopathy

RecruitingNCT04776993

University of PisaGraves' Orbitopathy

Start: 2023-03-02End: 2026-03-01Target: 52Updated: 2023-03-17

Effect of Hyperthyroidism and Its Treatment in Graves' Disease to Early Marker of Atherosclerosis

CompletedNCT05118542

Indonesia UniversityAtherosclerosis of Artery, Graves Disease, Hyperthyroidism +1

Start: 2019-01-01End: 2020-08-01Updated: 2021-11-12

Phase 4

Antithyroid Drugs During Radioiodine Therapy

CompletedNCT00150137

Odense University HospitalGraves Disease, Toxic Nodular Goitre

Start: 2003-01-31End: 2004-12-31Target: 80Updated: 2006-02-03

Block-replacement Therapy During Radioiodine Therapy

CompletedNCT00150124

Steen BonnemaGraves' Disease, Toxic Nodular Goitre

Start: 2003-01-31End: 2009-03-31Updated: 2013-12-04

Adjuvant Treatment of Graves´ Ophthalmopathy With NSAID (aGO Study)

CompletedNCT01458600

Mikael LantzGraves´ Disease

Start: 2006-09-30End: 2016-02-29Updated: 2016-02-24

Cardiopulmonary Capacity in Elderly With Different Ranges of Serum Thyroid Stimulating Hormone

NCT01849861

Universidade Federal do Rio de JaneiroHealthy

Start: 2011-09-30End: 2014-09-30Target: 200Updated: 2013-05-13

Effects of Different Treatment Schemes on the Regulation and Recurrence of Graves' Disease

RecruitingNCT05461820

The First Affiliated Hospital with Nanjing Medical UniversityDrug Withdrawal, Graves Disease, Relapse +1

Start: 2018-05-01End: 2030-07-31Target: 240Updated: 2023-12-11

Unknown Phase

Evaluation of Optimal Time of Methimazole Discontinuation Before Radio-iodine Therapy in Hyperthyroid Grave's Patients

CompletedNCT01560299

Mashhad University of Medical SciencesGraves Disease

Start: 2010-02-28End: 2012-01-31Updated: 2012-03-22

Bromocriptine and Pentoxifylline in Ophthalmopathy Autoimmune Treatment

TerminatedNCT01893450

Instituto Nacional de Ciencias Medicas y Nutricion Salvador ZubiranGraves Ophthalmopathy

Start: 2008-06-30End: 2013-06-30Updated: 2013-07-09

Characteristics of Islet β-cell Functions in Chinese Patients With Graves' Disease

CompletedNCT02376088

Weikai HouGraves Disease

Start: 2011-06-30End: 2014-06-30Updated: 2015-03-03

Treatment of Graves' Hyperthyroidism With Selenium Plus Methimazole

CompletedNCT02727738

University of PisaGraves' Disease

Start: 2014-01-31End: 2015-12-31Updated: 2016-04-06

AI-Based Wearable Monitoring (Glandy HYPER) for Antithyroid Drug Dose Adjustment in Graves' Disease

Not yet recruitingNCT07857421

THYROSCOPE INC.Graves Disease, Hyperthyroidism, Thyrotoxicosis

Start: 2026-10-20End: 2027-07-31Target: 30Updated: 2026-10-05

Related Papers

Targeting glioma stem cells with thyroid hormone suppression: Phase 1/2 trial of methimazole in patients with progressive grade 4 gliomas.

Journal of Clinical Oncology2024-06-01

The Effects of Anti-thyroid Drugs on Lipoproteins and Insulin Resistance in Graves’ Disease: A Randomized Clinical Trial

Journal of Lipid and Atherosclerosis2024-01-012 citations