LUM001

DRUG5 trials

Sponsors

Mirum Pharmaceuticals, Inc.

Conditions

Alagille SyndromePBCPrimary Biliary CirrhosisPrimary Sclerosing Cholangitis (PSC)

Phase 2

Safety and Efficacy Study of LUM001 in the Treatment of Cholestatic Liver Disease in Patients With Alagille Syndrome

CompletedNCT01903460

Mirum Pharmaceuticals, Inc.Alagille Syndrome

Start: 2013-08-31End: 2015-03-31Updated: 2019-03-28

Phase 2 Study to Evaluate LUM001 in Combination With Ursodeoxycholic Acid in Patients With Primary Biliary Cirrhosis

CompletedNCT01904058

Mirum Pharmaceuticals, Inc.PBC, Primary Biliary Cirrhosis

Start: 2013-08-31End: 2015-04-30Updated: 2019-03-27

Evaluation of LUM001 in the Reduction of Pruritus in Alagille Syndrome

CompletedNCT02057692

Mirum Pharmaceuticals, Inc.Alagille Syndrome

Start: 2014-11-24End: 2016-11-16Updated: 2019-03-26

Open Label Study to Evaluate Safety and Efficacy of LUM001 in Patients With Primary Sclerosing Cholangitis

CompletedNCT02061540

Mirum Pharmaceuticals, Inc.Primary Sclerosing Cholangitis (PSC)

Start: 2014-03-31End: 2016-02-29Updated: 2019-03-29

An Open-label Study to Evaluate the Long-term Safety and Tolerability of LUM001 in Patients With Primary Biliary Cirrhosis

WithdrawnNCT02321306

Mirum Pharmaceuticals, Inc.Primary Biliary Cirrhosis

Start: 2015-05-31End: 2018-03-31Updated: 2019-03-19

Related Papers

Safety, tolerability, and efficacy of maralixibat in adults with primary sclerosing cholangitis: Open-label pilot study

Hepatology Communications2023-05-1535 citations

Use of funded multicenter prospective longitudinal databases to inform clinical trials in rare diseases—Examination of cholestatic liver disease in Alagille syndrome

Hepatology Communications2022-05-045 citations

Placebo‐Controlled Randomized Trial of an Intestinal Bile Salt Transport Inhibitor for Pruritus in Alagille Syndrome

Hepatology Communications2018-09-2498 citations

BAT117213: Ileal bile acid transporter (IBAT) inhibition as a treatment for pruritus in primary biliary cirrhosis: study protocol for a randomised controlled trial

BMC Gastroenterology2016-07-1839 citations