Luer lock applicator

DEVICE11 trials

Sponsors

Heron Therapeutics

Conditions

AnalgesiaBunionsLumbar LaminectomyMultimodal AnalgesiaPost-Operative PainPostoperative PainTotal Shoulder Arthroplasty

Phase 1

Dose-Escalation Study of HTX-034 Following Bunionectomy

CompletedNCT04398329

Heron TherapeuticsBunions, Postoperative Pain

Start: 2020-05-08End: 2021-07-15Updated: 2026-06-09

Phase 2

Phase 2 Herniorrhaphy Study for Opioid Elimination

CompletedNCT03695367

Heron TherapeuticsPostoperative Pain

Start: 2018-10-01End: 2018-12-15Updated: 2026-03-02

Phase 2 Bunionectomy HTX-011 Administration Study

CompletedNCT03718039

Heron TherapeuticsPostoperative Pain

Start: 2018-10-24End: 2019-03-11Updated: 2026-03-02

Pediatric Postoperative Analgesia Herniorrhaphy Study

WithdrawnNCT03922048

Heron TherapeuticsAnalgesia

Start: 2023-07-01End: 2025-12-01Updated: 2026-05-12

HTX-011 Administration Study in Planned Caesarean Section Procedure

CompletedNCT03955211

Heron TherapeuticsAnalgesia

Start: 2019-06-24End: 2021-12-27Updated: 2022-03-14

HTX-011 in Spinal Surgery

CompletedNCT04911062

Heron TherapeuticsLumbar Laminectomy, Post-Operative Pain

Start: 2022-04-07End: 2022-08-26Updated: 2023-06-12

Phase 3

Study of Post-Herniorrhaphy Non-opioid MMA Regimens

CompletedNCT03907176

Heron TherapeuticsAnalgesia

Start: 2019-04-04End: 2021-11-22Updated: 2026-06-04

Total Knee Arthroplasty (TKA) Study of HTX-011 in an Multimodal Analgesic Regimen (MMA) Regimen

CompletedNCT03974932

Heron TherapeuticsAnalgesia

Start: 2019-06-05End: 2021-01-07Updated: 2026-03-02

Phase 4

A Multi-surgery Assessment of ZYNRELEF (HTX-011), AMAZE. Master Protocol HTX-011-401.

Heron TherapeuticsAnalgesia

Start: 2021-10-12End: 2024-06-30Target: 90Updated: 2023-10-26

A Multi-surgery Assessment of ZYNRELEF (HTX-011), AMAZE.

CompletedNCT06109415

Heron TherapeuticsMultimodal Analgesia, Postoperative Pain, Total Shoulder Arthroplasty

Start: 2021-10-20End: 2022-07-29Updated: 2023-10-31

A Multi-surgery Assessment of ZYNRELEF (HTX-011), AMAZE

CompletedNCT06109428

Heron TherapeuticsAnalgesia

Start: 2021-10-12End: 2022-04-07Updated: 2023-10-31

Related Papers

HTX-011 in Combination with Multimodal Analgesic Regimen Minimized Severe Pain and Opioid Use after Total Knee Arthroplasty in an Open-Label Study

The Journal of Knee Surgery2022-06-103 citations

Opioid-Free Recovery After Hernia Repair with HTX-011 as the Foundation of a Non-Opioid, Multimodal Analgesia Regimen in a Real-World Setting: A Randomized, Open-Label Study.

2021-07-276 citations