Low-Dose Naltrexone

DRUG8 trials

Conditions

AgingAlcohol Use, UnspecifiedBladder Pain SyndromeChronic PainFibromyalgiaFrontal Fibrosing AlopeciaHIV InfectionsInterstitial Cystitis

Phase 2

St. PETERsburg Pain and Alcohol Intervention With Naltrexone and Gabapentin

CompletedNCT04052139

Boston Medical CenterAlcohol Use, Unspecified, Chronic Pain, HIV Infections

Start: 2021-01-25End: 2021-12-15Updated: 2022-11-10

Oral Low-Dose Naltrexone for Lichen Planopilaris and Frontal Fibrosing Alopecia

CompletedNCT04409041

Washington University School of MedicineFrontal Fibrosing Alopecia, Lichen Planopilaris

Start: 2019-09-01End: 2020-12-31Updated: 2021-12-30

LDN and tDCS in Fibromyalgia

CompletedNCT04502251

Centro Universitario La SalleFibromyalgia

Start: 2018-08-01End: 2020-07-01Updated: 2020-08-06

Low-dose Naltrexone for Post-COVID Fatigue Syndrome

CompletedNCT05430152

Luis NaculPost-Viral Fatigue Syndrome

Start: 2024-01-15End: 2026-02-28Updated: 2026-03-20

LIFT: Life Improvement Trial

RecruitingNCT06366724

Brigham and Women's HospitalLong COVID, ME/CFS, PASC

Start: 2024-09-10End: 2026-11-30Target: 160Updated: 2025-10-22

Phase 4

IC PaIN Trial: Interstitial Cystitis Pain Improvement With Naltrexone

TerminatedNCT04313972

Endeavor HealthBladder Pain Syndrome, Interstitial Cystitis, Low-dose Naltrexone +3

Start: 2021-09-07End: 2023-02-23Updated: 2025-03-07

Cost-utility and Physiological Effects of LDN in Patients With Fibromyalgia

Active, not recruitingNCT04739995

Fundació Sant Joan de DéuRandomized Controlled Trial

Start: 2022-06-01End: 2024-12-31Updated: 2024-04-22

Unknown Phase

The Effects of Low Dose Naltrexone (LDN) on Diseases of Aging

WithdrawnNCT05307627

AgelessRxAging

Start: 2022-03-14End: 2023-12-14Updated: 2024-08-06

Related Papers

Pyridostigmine and low-dose naltrexone for ME/CFS: study protocol for the Life Improvement Trial (LIFT), a randomized, double-blind, placebo-controlled clinical trial

Trials2026-08-12

Low-dose naltrexone for post-COVID fatigue syndrome: a study protocol for a double-blind, randomised trial in British Columbia

BMJ Open2024-05-0120 citations

What is quality in long covid care? Lessons from a national quality improvement collaborative and multi-site ethnography.

2024-04-1519 citations

Association of low-dose naltrexone and transcranial direct current stimulation in fibromyalgia: a randomized, double-blinded, parallel clinical trial.

2022-08-1823 citations

Study protocol for a randomised, double-blinded, placebo-controlled phase III trial examining the add-on efficacy, cost–utility and neurobiological effects of low-dose naltrexone (LDN) in patients with fibromyalgia (INNOVA study)

BMJ Open2022-01-0114 citations