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Low Intensity Focused Ultrasound

DEVICE11 trials

Sponsors

Virginia Polytechnic Institute and State University, Ocean State Research Institute, Inc., University of British Columbia, University of California, San Francisco, Laureate Institute for Brain Research, Inc.

Conditions

Alcohol Use DisorderChronic PainDepressionElectrodes, ImplantedGeneralized Anxiety DisorderLow Intensity Focussed UltrasoundMemoryMild Cognitive Impairment (MCI)

Phase 2

SONATA LIFU for OCD
RecruitingNCT07728994
University of PennsylvaniaObsessive Compulsive Disorder
Start: 2026-07-01End: 2028-10-31Target: 40Updated: 2026-07-27

Unknown Phase

Investigation of Low-intensity Focused Ultrasound for Human Pain Management
CompletedNCT05145426
Virginia Polytechnic Institute and State UniversityChronic Pain
Start: 2022-02-04End: 2025-07-23Updated: 2026-05-27
Low Intensity Focused Ultrasound: a New Paradigm for Depression and Anxiety
CompletedNCT05147142
Ocean State Research Institute, Inc.Depression
Start: 2021-09-28End: 2026-03-04Updated: 2026-07-24
Using Low Intensity Focused Ultrasound to Modulate Deep Brain Areas for Tremor Control in Parkinson's Disease Patients.
CompletedNCT06259708
University of British ColumbiaParkinson Disease
Start: 2024-03-01End: 2025-06-17Updated: 2026-04-30
Ultrasound Neuromodulation of the Brain for Alcohol Use Disorder
RecruitingNCT06518785
University of California, San FranciscoAlcohol Use Disorder
Start: 2025-01-07End: 2030-09-01Target: 25Updated: 2026-09-11
Study of Low-intensity Focused Ultrasound Effects on Human Memory
Enrolling by invitationNCT06628193
Virginia Polytechnic Institute and State UniversityMemory
Start: 2024-11-18End: 2027-05-01Target: 80Updated: 2026-03-31
LIFU Mechanisms for PTSD in Healthcare Workers
RecruitingNCT07164105
Laureate Institute for Brain Research, Inc.PTSD and Trauma-related Symptoms
Start: 2025-12-29End: 2028-08-01Target: 66Updated: 2026-04-20
Mapping LIFU Responses Using iEEG Recordings
Enrolling by invitationNCT07518927
University of PennsylvaniaElectrodes, Implanted, Low Intensity Focussed Ultrasound
Start: 2026-03-04End: 2031-03-04Target: 30Updated: 2026-04-09
OCD LIFU Target Engagement
RecruitingNCT07558148
University of PennsylvaniaObsessive Compulsive Disorder (OCD)
Start: 2026-03-04End: 2027-05-19Target: 10Updated: 2026-07-24
LIFU for Chronic Pain and Generalized Anxiety Disorder
Not yet recruitingNCT07686354
Virginia Polytechnic Institute and State UniversityChronic Pain, Generalized Anxiety Disorder
Start: 2026-10-01End: 2027-12-01Target: 10Updated: 2026-09-11
Mild Cognitive Impairment and Neuromodulation
Enrolling by invitationNCT07691918
Virginia Polytechnic Institute and State UniversityMild Cognitive Impairment (MCI)
Start: 2026-10-01End: 2028-12-01Target: 40Updated: 2026-08-21