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Loteprednol etabonate

DRUG12 trials

Sponsors

Bausch & Lomb Incorporated, Southern California College of Optometry at Marshall B. Ketchum University, Khon Kaen University, Cornea Research Foundation of America, Edward Holland, MD

Conditions

Allergic ConjunctivitisCataractConjunctivitisConjunctivitis, Giant PapillaryConjunctivitis, Seasonal AllergicCorneal EdemaDry EyeDry Eye Disease

Phase 1

Evaluation of the Safety, Systemic Pharmacokinetics, and Tolerability of Single and Repeat Ocular Installations
CompletedNCT03098953
Bausch & Lomb IncorporatedHealthy
Start: 2017-04-10End: 2017-05-12Updated: 2017-05-18

Phase 3

Loteprednol Etabonate in an Ophthalmic Base vs Vehicle for the Treatment of Inflammation Following Cataract Surgery
CompletedNCT00699153
Bausch & Lomb IncorporatedOcular Inflammation
Start: 2008-06-30End: 2009-06-30Updated: 2015-03-24
Loteprednol Etabonate Versus Vehicle for the Treatment of Inflammation and Pain Following Cataract Surgery
CompletedNCT01010633
Bausch & Lomb IncorporatedInflammation, Pain
Start: 2009-11-30End: 2010-08-31Updated: 2012-01-09
Evaluation of Loteprednol Etabonate Versus Vehicle for the Treatment of Inflammation and Pain Following Cataract Surgery
CompletedNCT01060072
Bausch & Lomb IncorporatedInflammation, Pain
Start: 2010-02-28End: 2010-10-31Updated: 2012-01-13
Loteprednol vs Prednisolone for the Treatment of Intraocular Inflammation Following Cataract Surgery in Children.
CompletedNCT01475643
Bausch & Lomb IncorporatedCataract
Start: 2013-06-30End: 2017-07-31Updated: 2019-06-11

Phase 4

Safety and Efficacy of Zylet vs Lotemax, Tobramycin and Vehicle in Pediatric Blepharoconjunctivitis
CompletedNCT00705159
Bausch & Lomb IncorporatedConjunctivitis
Start: 2008-06-30End: 2010-05-31Updated: 2015-03-24
A Study to Evaluate the Safety and Efficacy of Lotemax Ophthalmic Suspension 0.5%
CompletedNCT01437982
Bausch & Lomb IncorporatedConjunctivitis, Giant Papillary, Conjunctivitis, Seasonal Allergic, Inflammation
Start: 2010-08-05End: 2015-10-19Target: 140Updated: 2019-11-19
Bepreve vs. Alrex in Subjects With Moderate to Severe Allergic Conjunctivitis
CompletedNCT01443442
Southern California College of Optometry at Marshall B. Ketchum UniversityAllergic Conjunctivitis
Start: 2011-10-31End: 2012-12-31Updated: 2019-08-06
Comparison the Effects of Dexamethasone and Loteprednol on Epithelial Healing
CompletedNCT01724892
Khon Kaen UniversityEpithelial Defect After Phototherapeutic Keratectomy
Start: 2012-11-30End: 2013-09-30Updated: 2014-03-17
Comparison of Corticosteroid Dosing Regimens After Endothelial Keratoplasty
CompletedNCT01853696
Cornea Research Foundation of AmericaCorneal Edema, Fuchs' Dystrophy
Start: 2013-03-31End: 2015-01-31Updated: 2015-05-15
A Phase IV, Randomized, Parallel Group, Investigator-Masked Evaluation of the Effect of Loteprednol Etabonate Ophthalmic Gel 0.5% on the Initiation of Dry Eye Treatment With Restasis®
WithdrawnNCT02028312
Edward Holland, MDDry Eye Disease
Start: 2014-01-31End: 2016-06-30Updated: 2015-03-18
Comparing Treatment of Dry Eye With Intracanalicular Dexamethasone, Restasis, and/or Lotemax
CompletedNCT04555694
Thomas Chester, ODDry Eye
Start: 2020-10-01End: 2022-02-16Updated: 2023-10-11

Related Papers

Loteprednol Etabonate 0.5% Gel Vs. Prednisolone Acetate 1% Solution After Descemet Membrane Endothelial Keratoplasty
Cornea2015-05-2883 citations