lipoic acid

DRUG14 trials

Conditions

AdrenomyeloneuropathyAllergic RhinitisAlzheimer's DiseaseAsthmaCIDPChronic Inflammatory Demyelinating PolyneuropathyDementiaDiabetes Mellitus, Type 2

Phase 1

Fish Oil and Alpha Lipoic Acid in Treating Alzheimer's Disease

CompletedNCT00090402

Oregon Health and Science UniversityAlzheimer's Disease, Dementia, Hyperlipidemia +2

Start: 2004-04-30End: 2007-08-31Updated: 2017-07-21

Defining the Anti-inflammatory Role of Lipoic Acid in Multiple Sclerosis

CompletedNCT00997438

Portland VA Medical CenterMultiple Sclerosis

Start: 2010-08-31End: 2013-12-31Updated: 2017-01-26

Lipoic Acid as a Treatment for Acute Optic Neuritis

CompletedNCT01294176

Oregon Health and Science UniversityOptic Neuritis

Start: 2011-01-31End: 2016-11-30Updated: 2019-04-26

Treatment With Human Umbilical Cord Mesenchymal Stem Cells for Refractory Diabetic Peripheral Neuropathy

NCT05507697

Wuhan Central HospitalDiabetic Peripheral Neuropathy Type 2

Start: 2022-05-19End: 2024-05-31Target: 42Updated: 2022-08-19

Phase 2

Antioxidant Functions of Lipoic Acid

CompletedNCT00065624

National Center for Complementary and Integrative Health (NCCIH)Hypercholesterolemia

Start: 2003-11-30End: 2007-07-31Target: 16Updated: 2007-10-02

The Effects of Lipoic Acid on Glycaemic Control in Type 2 Diabetes

WithdrawnNCT00398892

University of EdinburghDiabetes Mellitus, Type 2

Start: 2009-12-31End: 2011-01-31Updated: 2024-05-29

Lipoic Acid to Treat Chronic Inflammatory Demyelinating Polyneuropathy

CompletedNCT00962429

Oregon Health and Science UniversityChronic Inflammatory Demyelinating Polyneuropathy, CIDP

Start: 2009-02-28End: 2013-01-31Updated: 2020-08-19

Lipoic Acid for Secondary Progressive Multiple Sclerosis (MS)

CompletedNCT01188811

VA Office of Research and DevelopmentMultiple Sclerosis, Chronic Progressive

Start: 2010-10-31End: 2015-08-31Updated: 2017-02-02

Efficacy and Safety Study of Thioctacid Oral Tablets 600mg to Treat Chinese Diabetic Patients With Distal Symmetric Polyneuropathy

NCT01224353

NovaMed Pharmaceuticals Inc.Diabetics

Start: 2010-11-30End: 2011-07-31Target: 200Updated: 2010-10-21

A Clinical Trial for AMN: Validation of Biomarkers of Oxidative Stress, Efficacy and Safety of a Mixture of Antioxidants

CompletedNCT01495260

Pujol, Aurora, M.D.Adrenomyeloneuropathy

Start: 2011-09-30End: 2013-11-30Updated: 2019-03-11

Lipoic Acid for Progressive Multiple Sclerosis (MS)

CompletedNCT03161028

VA Office of Research and DevelopmentMultiple Sclerosis

Start: 2018-08-17End: 2024-06-30Updated: 2025-03-03

Phase 4

Vaginal Administration of ALA vs Progesterone for the Subchorionic Hematoma Treatment

CompletedNCT02601898

Azienda USL FerraraMiscarriage, Subchorionic Hematoma in the First Trimester Pregnancy

Start: 2015-01-31Updated: 2016-01-08

Unknown Phase

Effects of Lipoic Acid on Oxidative, Inflammatory and Functional Markers in Asthmatic Patients

CompletedNCT01221350

Centro Universitario de Ciencias de la Salud, MexicoAllergic Rhinitis, Asthma

Start: 2010-11-30End: 2012-08-31Updated: 2013-11-08

Vitamin E or Lipoic Acid on Serum Oxyphytosterol Concentrations

NCT01984567

Maastricht University Medical CenterOxidative Stress

Start: 2013-04-30End: 2014-01-31Updated: 2013-11-14

2025-12-15

Processing speed and memory test performance are associated with different brain region volumes in Veterans and others with progressive multiple sclerosis

Frontiers in Neurology2023-06-087 citations

Activating cannabinoid receptor 2 preserves axonal health through GSK-3β/NRF2 axis in adrenoleukodystrophy.

2022-07-016 citations

Biomarker Identification, Safety, and Efficacy of High-Dose Antioxidants for Adrenomyeloneuropathy: a Phase II Pilot Study.

2019-10-0134 citations

Effects of lipoic acid on walking performance, gait, and balance in secondary progressive multiple sclerosis.

2018-09-2223 citations

Lipoic Acid Stimulates cAMP Production in Healthy Control and Secondary Progressive MS Subjects.

2017-11-1515 citations

Lipoic acid in secondary progressive MS: A randomized controlled pilot trial.

2017-06-2894 citations

Tolerability in the elderly population of high-dose alpha lipoic acid: a potential antioxidant therapy for the eye

Clinical ophthalmology2016-09-0122 citations