Lifitegrast
Sponsors
Shire, University of Alabama at Birmingham, Lifelong Vision Foundation, EV Clinical Trials, MDbackline, LLC
Conditions
Allergic ConjunctivitisContact LensContact Lens ComplicationContact Lens DiscomfortContact Lens Dry EyeContact Lens DrynessDry EyeDry Eye Disease
Phase 1
Phase 2
Efficacy Study to Evaluate the Effectiveness of 3 Concentrations of SAR 1118 in Allergic Conjunctivitis
CompletedNCT00882687
Start: 2009-04-24End: 2009-05-10Updated: 2021-06-11
A Study Evaluating the Efficacy of SAR 1118 (0.1%, 1.0%, 5.0%) Ophthalmic Solution in Subjects With Dry Eye Conducted in a Controlled Adverse Environment (CAE)
CompletedNCT00926185
Start: 2009-08-03End: 2010-02-18Updated: 2021-08-09
A Study Evaluating the Safety and Efficacy of a Fixed-Dose Combination for Dry Eye Disease
CompletedNCT07128628
Start: 2025-10-24End: 2026-05-28Updated: 2026-07-14
Phase 3
Safety and Efficacy Study of SAR 1118 to Treat Dry Eye Conducted in a Controlled Adverse Environment (CAE) (OPUS-1)
CompletedNCT01421498
Start: 2011-08-29End: 2012-04-28Updated: 2021-06-11
Safety Study of Lifitegrast to Treat Dry Eye
CompletedNCT01636206
Start: 2012-10-16End: 2014-03-03Updated: 2021-06-11
A Phase 3 Study to Evaluate the Efficacy of Lifitegrast in Subjects With Dry Eye
CompletedNCT01743729
Start: 2012-12-07End: 2013-10-01Updated: 2021-06-23
A Study to Evaluate Efficacy and Safety of Lifitegrast in Subjects With Dry Eye (OPUS-3)
CompletedNCT02284516
Start: 2014-11-06End: 2015-10-05Updated: 2021-06-11
Phase 4
Effects of Xiidra on Closed Eye Tear Film Leukocytes in Dry Eye Disease
WithdrawnNCT03408015
Start: 2019-01-31End: 2019-01-30Updated: 2019-05-17
Use of 5.0% Lifitegrast Ophthalmic Solution for the Treatment of Dry Eye Disease in Contact Lens Wearers
WithdrawnNCT03431272
Start: 2018-11-01End: 2019-12-31Updated: 2018-10-25
Effect of Lifitegrast on Dry Eye Disease Signs and Symptoms
CompletedNCT03451396
Start: 2016-12-12End: 2018-03-15Updated: 2018-03-19
Lifitegrast 5% Ophthalmic Solution and Contact Lens Dryness
CompletedNCT03686878
Start: 2016-12-16End: 2017-07-14Updated: 2018-09-28
Clinical Efficacy of Two Topical Dry Eye Drops for Central Corneal Stain Clearing Over 90 Days
NCT04172961
Start: 2020-02-01End: 2022-12-01Target: 100Updated: 2022-10-20
Unknown Phase
The Effect Of Lifitegrast On Refractive Accuracy And Symptoms In Dry Eye Patients Undergoing Cataract Surgery
CompletedNCT03866629
Start: 2018-12-20End: 2019-10-29Updated: 2020-03-19
Examining the Clinical Characteristics, Treatment Patterns, Real-world Effectiveness, and Healthcare Resource Utilization of Patients With Dry Eye Disease
WithdrawnNCT05857748
Start: 2023-07-31End: 2024-12-30Updated: 2023-09-01