levodopa-carbidopa

DRUG8 trials

Sponsors

Shahid Beheshti University of Medical Sciences, Osmotica Pharmaceutical US LLC, AbbVie, Beirut Eye Specialist Hospital, Centre Hospitalier Universitaire Vaudois

Conditions

Drug EffectNonarteritic Anterior Ischemic Optic NeuropathyParkinson DiseaseParkinson's DiseaseRetinitis PigmentosaSpinal Cord Injuries

Phase 1

A Pharmacokinetic Study of Levodopa and Carbidopa Intestinal Gel in Subjects With Advanced Parkinson's Disease

CompletedNCT01484990

AbbVieParkinson Disease

Start: 2010-04-30End: 2010-09-30Updated: 2017-11-21

Acute Effects of Pharmacological Neuromodulation on Leg Motor Activity in Patients With SCI Treated With EES

CompletedNCT04052776

Centre Hospitalier Universitaire VaudoisDrug Effect, Spinal Cord Injuries

Start: 2020-09-11End: 2023-10-04Updated: 2023-10-05

Phase 2

Efficacy, Safety, and Pharmacokinetics/Pharmacodynamic Study of L-Dopa/Carbidopa To Treat Parkinson's Disease

CompletedNCT00558337

Osmotica Pharmaceutical US LLCParkinson's Disease

Start: 2007-11-30End: 2008-12-31Updated: 2009-01-14

Studying a Potential Protective Effect of L-Dopa on Retinitis Pigmentosa

Beirut Eye Specialist HospitalRetinitis Pigmentosa

Start: 2016-06-30End: 2021-06-30Target: 50Updated: 2016-07-19

Clinical Study to Evaluate the Possible Efficacy of Metformin in Patients With Parkinson's Disease

CompletedNCT05781711

Tanta UniversityParkinson Disease

Start: 2023-01-06End: 2025-01-20Updated: 2026-03-13

Montelukast in Parkinson Disease

RecruitingNCT06113640

Mostafa BahaaParkinson Disease

Start: 2023-11-05End: 2026-12-20Target: 60Updated: 2026-03-13

Role of Silymarin in Neuroprotection and Symptom Management in Parkinson's Disease

RecruitingNCT07001150

Tanta UniversityParkinson Disease

Start: 2025-05-10End: 2026-05-30Target: 50Updated: 2025-09-10

Phase 4

Effect of Levodopa-Carbidopa on Visual Function in Patients With Recent-Onset Nonarteritic Anterior Ischemic Optic Neuropathy

CompletedNCT00432393

Shahid Beheshti University of Medical SciencesNonarteritic Anterior Ischemic Optic Neuropathy

Start: 2002-06-30End: 2003-04-30Updated: 2008-10-20

Related Papers

Randomized, double-blind, placebo-controlled pilot study of metformin as an adjunctive therapy in Parkinson’s disease

Frontiers in Pharmacology2025-05-023 citations