Lenograstim
Sponsors
Fondazione Gimema Franco Mandelli Onlus, Genenta Science S.p.A., Orchard Therapeutics (Europe) Limited, University Of Cologne, Fondazione Telethon Ets
Conditions
Acute Myeloid LeukemiaAcute Myeloid Leukemia (AML)Adult Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia.Brain and Central Nervous System TumorsCastrate Resistant Prostate CancerDiffuse Large B-Cell LymphomaExtragonadal Germ Cell TumorG-CSF, Multiple Myeloma, Febrile Episode, Filgrastim, Leograstim
Phase 1
Bortezomib Plus CHOP Every 2 Weeks for Advanced Stage DLBCL
CompletedNCT00379574
Start: 2006-09-30End: 2011-01-31Updated: 2013-03-15
Gemcitabine, Paclitaxel, Ifosfamide, and Cisplatin in Treating Patients With Progressive or Relapsed Metastatic Germ Cell Tumors
NCT00551122
Start: 2006-11-30Target: 23Updated: 2013-01-23
Donation of Whole Blood by Healthy Volunteers After Mobilisation by Haematopoietic Growth Factor (Rhu-G-CSF = Granocyte)
RecruitingNCT05594433
Start: 2015-09-10End: 2025-01-31Target: 40Updated: 2024-07-10
A phase I/II study evaluating safety and efficacy of autologous hematopoietic stem and progenitor cells genetically modified with IDUA lentiviral vector encoding for the human α-L-iduronidase gene for the treatment of patients affected by Mucopolysaccharidosis Type I, Hurler variant
Active, not recruitingCTIS2024-514870-29-00
Start: 2018-05-14Target: 8Updated: 2025-10-20
An open-label phase 1/2 study to evaluate the safety, biological response and efficacy of a single dose of Temferon (autologous CD34+-enriched hematopoietic stem and progenitors cells genetically modified with human Interferon-α2) in patients with metastatic renal cell carcinoma
RecruitingCTIS2024-512898-27-00
Start: 2024-10-22Target: 12Updated: 2025-09-17
Phase 2
Predictive Value of the Cytocapacity Test Patients With Lymphoproliferative Diseases and High-dose Therapy
CompletedNCT01085058
Start: 2003-05-31End: 2004-12-31Updated: 2010-03-11
Trial Evaluating Induction Therapy With Idarubicin and Etoposide Plus Sequential or Concurrent Azacitidine and Maintenance Therapy With Azacitidine
CompletedNCT01180322
Start: 2010-11-30End: 2016-10-02Updated: 2020-12-31
A Phase II Study Evaluating Intravenous Melphalan With Autologous Whole Blood Stem Cell Transplantation Over Three Cycles In Patients With Castration-Resistant Prostate Cancer (MEL-CAP)
TerminatedNCT01907009
Start: 2013-01-31End: 2016-12-22Updated: 2023-04-19
Combination of Ponatinib Plus Chemotherapy As Frontline Treatment For Patients With BCR/ABL1-Like Acute Lymphoblastic Leukemia (BCR/ABL1-Like ALL) - BALLik. ALL2922
RecruitingCTIS2023-510240-20-00
Start: 2022-10-05Target: 32Updated: 2025-05-13
Daratumumab in adults with Very High-Risk T-Lineage Acute Lymphoblastic Leukemia (ALL) Treated According to the ALL National Treatment Program (DARATALL-VHR)- GIMEMA ALL3024
RecruitingCTIS2024-511627-34-00
Start: 2024-10-17Target: 31Updated: 2025-12-23
Phase 3
Dose Dense Chemotherapy + Rituximab +/-Intensified High Dose Chemoimmunotherapy With Support of Peripheral Autologous Stem Cell in Diffuse Large B-Cell Lymphoma
NCT00499018
Start: 2006-01-31End: 2013-09-30Target: 399Updated: 2011-02-15
Study on the Incidence of Febrile Episodes During Stem Cells Collection After Chemotherapy in Patients With Multiple Myeloma
NCT00932217
Start: 2004-12-31Updated: 2009-07-03
Azacytidine (Vidaza®) Versus Fludarabine and Cytarabine (Fluga Scheme) in Elderly Patients With Newly Diagnosed Acute Myeloid Leukemia
CompletedNCT02319135
Start: 2014-10-31End: 2019-10-28Updated: 2020-04-06
Prospective multicenter clinical trial for risk estimation and treatment stratification in low and intermediate risk neuroblastoma patients - NB2015-LR
Not yet recruitingCTIS2024-517295-37-00
Target: 280Updated: 2024-10-25
A Single Arm, Open Label Clinical Study of Hematopoietic Stem Cell Gene Therapy with Cryopreserved Autologous CD34+ Cells Transduced with Lentiviral Vector encoding WAS cDNA in Subjects with Wiskott-Aldrich Syndrome (WAS)
Not yet recruitingCTIS2024-517792-20-00
Target: 9Updated: 2025-09-23
Unknown Phase
Use of granulocyte colony-stimulating factor (Lenograstim) for the treatment of unexplained recurrent miscarriage
Active, not recruitingJPRN-UMIN000007011
Start: 2012-02-01Target: 20Updated: 2025-07-18
Efficacy of Granulocyte-Colony Stimulating Factor (G-CSF)
NCT03498248
Start: 2018-02-19End: 2019-08-31Target: 155Updated: 2018-04-13