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Lenograstim

DRUG17 trials

Sponsors

Fondazione Gimema Franco Mandelli Onlus, Genenta Science S.p.A., Orchard Therapeutics (Europe) Limited, University Of Cologne, Fondazione Telethon Ets

Conditions

Acute Myeloid LeukemiaAcute Myeloid Leukemia (AML)Adult Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia.Brain and Central Nervous System TumorsCastrate Resistant Prostate CancerDiffuse Large B-Cell LymphomaExtragonadal Germ Cell TumorG-CSF, Multiple Myeloma, Febrile Episode, Filgrastim, Leograstim

Phase 1

Bortezomib Plus CHOP Every 2 Weeks for Advanced Stage DLBCL
CompletedNCT00379574
Asan Medical CenterLymphoma, B-Cell, Lymphoma, Large-Cell, Diffuse
Start: 2006-09-30End: 2011-01-31Updated: 2013-03-15
Gemcitabine, Paclitaxel, Ifosfamide, and Cisplatin in Treating Patients With Progressive or Relapsed Metastatic Germ Cell Tumors
NCT00551122
University of SouthamptonBrain and Central Nervous System Tumors, Extragonadal Germ Cell Tumor, Ovarian Cancer +1
Start: 2006-11-30Target: 23Updated: 2013-01-23
Donation of Whole Blood by Healthy Volunteers After Mobilisation by Haematopoietic Growth Factor (Rhu-G-CSF = Granocyte)
RecruitingNCT05594433
CellProtheraHealthy Volunteers
Start: 2015-09-10End: 2025-01-31Target: 40Updated: 2024-07-10
A phase I/II study evaluating safety and efficacy of autologous hematopoietic stem and progenitor cells genetically modified with IDUA lentiviral vector encoding for the human α-L-iduronidase gene for the treatment of patients affected by Mucopolysaccharidosis Type I, Hurler variant
Active, not recruitingCTIS2024-514870-29-00
Orchard Therapeutics (Europe) LimitedMucopolysaccharidosis type I Hurler
Start: 2018-05-14Target: 8Updated: 2025-10-20
An open-label phase 1/2 study to evaluate the safety, biological response and efficacy of a single dose of Temferon (autologous CD34+-enriched hematopoietic stem and progenitors cells genetically modified with human Interferon-α2) in patients with metastatic renal cell carcinoma
RecruitingCTIS2024-512898-27-00
Genenta Science S.p.A.Patients with locally advanced/metastatic renal cell carcinoma with evidence of disease progression following standard of care treatment
Start: 2024-10-22Target: 12Updated: 2025-09-17

Phase 2

Predictive Value of the Cytocapacity Test Patients With Lymphoproliferative Diseases and High-dose Therapy
CompletedNCT01085058
WiSP Wissenschaftlicher Service Pharma GmbHHodgkin's Disease, Multiple Myelomas, Non-Hodgkin Lymphomas
Start: 2003-05-31End: 2004-12-31Updated: 2010-03-11
Trial Evaluating Induction Therapy With Idarubicin and Etoposide Plus Sequential or Concurrent Azacitidine and Maintenance Therapy With Azacitidine
CompletedNCT01180322
University of UlmAcute Myeloid Leukemia (AML)
Start: 2010-11-30End: 2016-10-02Updated: 2020-12-31
A Phase II Study Evaluating Intravenous Melphalan With Autologous Whole Blood Stem Cell Transplantation Over Three Cycles In Patients With Castration-Resistant Prostate Cancer (MEL-CAP)
TerminatedNCT01907009
Barts & The London NHS TrustCastrate Resistant Prostate Cancer
Start: 2013-01-31End: 2016-12-22Updated: 2023-04-19
Combination of Ponatinib Plus Chemotherapy As Frontline Treatment For Patients With BCR/ABL1-Like Acute Lymphoblastic Leukemia (BCR/ABL1-Like ALL) - BALLik. ALL2922
RecruitingCTIS2023-510240-20-00
Fondazione Gimema Franco Mandelli OnlusAdult Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia.
Start: 2022-10-05Target: 32Updated: 2025-05-13
Daratumumab in adults with Very High-Risk T-Lineage Acute Lymphoblastic Leukemia (ALL) Treated According to the ALL National Treatment Program (DARATALL-VHR)- GIMEMA ALL3024
RecruitingCTIS2024-511627-34-00
Fondazione Gimema Franco Mandelli OnlusVery High-Risk T-Lineage Acute Lymphoblastic Leukemia (ALL)
Start: 2024-10-17Target: 31Updated: 2025-12-23

Phase 3

Unknown Phase

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