LEMTRADA 12 mg concentrate for solution for infusion
Sponsors
Cellectis, Helse Bergen HF, St. Anna Childrens Cancer Research Institute GmbH, Fondazione Italiana Sclerosi Multipla Ente Del Terzo Settore/et S
Conditions
Langerhans Cell HistiocytosisMultiple sclerosisRelapsed or refractory B-cell Acute Lymphoblastic
LeukemiaRelapsed or refractory B-cell Non-Hodgkin lymphomaRelapsing Remitting Multiple Sclerosis
Phase 1
Open-label dose-finding and dose-expansion study to evaluate the safety, expansion, persistence, and clinical activity of UCART20x22 in subjects with relapsed or refractory B-cell Non-Hodgkin Lymphoma (B-NHL)
RecruitingCTIS2022-501607-27-00
Start: 2026-01-06Target: 48Updated: 2026-01-08
Open label dose-escalation and dose-expansion study to evaluate the safety, expansion, persistence and clinical activity of UCART22 (allogeneic engineered T-cells expressing Anti-CD22 Chimeric Antigen Receptor) in patients with relapsed or refractory CD22+ B-cell Acute Lymphoblastic Leukemia (B-ALL)
Active, not recruitingCTIS2022-502305-15-00
Start: 2025-11-26Target: 40Updated: 2025-11-26
Phase 2
LCH-IV International Collaborative Treatment Protocol for Children and Adolescents with Langerhans Cell Histiocytosis
Not yet recruitingCTIS2024-512676-36-00
Target: 1124Updated: 2024-10-14
NO EVIDENCE OF DISEASE ACTIVITY AFTER AUTOLOGOUS HAEMATOPOIETIC STEM CELL TRANSPLANTATION IN AGGRESSIVE MULTIPLE SCLEROSIS: THE NET-MS STUDY
RecruitingCTIS2024-515470-26-00
Start: 2024-10-31Target: 90Updated: 2025-11-17